STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (158 aa)    
Predicted Functional Partners:
purD
KEGG: bcr:BCAH187_A0372 2.0e-114 purD; phosphoribosylamine--glycine ligase K01945; Psort location: Cytoplasmic, score: 7.50; Belongs to the GARS family.
  
 0.999
purC
Phosphoribosylaminoimidazolesuccinocarboxamide synthase; KEGG: cst:CLOST_0334 6.4e-79 purC; phosphoribosylaminoimidazole-succinocarboxamide synthetase K01923; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.999
PurL
KEGG: ipo:Ilyop_2204 0. phosphoribosylformylglycinamidine synthase K01952; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.999
purK
Putative phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family.
 
 0.999
purM
KEGG: bmh:BMWSH_4950 9.6e-108 purM; Phosphoribosylformylglycinamidine cyclo-ligase; K01933 phosphoribosylformylglycinamidine cyclo-ligase; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.991
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
  
 0.990
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: hhd:HBHAL_1598 5.6e-151 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase.
 
  
 0.985
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
 
  
 0.984
PurB
Adenylosuccinate lyase; KEGG: erh:ERH_0935 1.2e-150 purB; adenylosuccinate lyase; K01756 adenylosuccinate lyase; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.974
fhs
KEGG: tsh:Tsac_0941 6.5e-173 Formate--tetrahydrofolate ligase; K01938 formate--tetrahydrofolate ligase; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.824
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
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