| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB57534.1 | KXB57535.1 | HMPREF3186_01719 | HMPREF3186_01720 | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein; KEGG: bbl:BLBBGE_302 0.0079 topA; DNA topoisomerase I K03168; Psort location: Cytoplasmic, score: 7.50. | 0.605 |
| KXB57535.1 | KXB57534.1 | HMPREF3186_01720 | HMPREF3186_01719 | Hypothetical protein; KEGG: bbl:BLBBGE_302 0.0079 topA; DNA topoisomerase I K03168; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | 0.605 |
| KXB57535.1 | KXB63363.1 | HMPREF3186_01720 | HMPREF3186_00150 | Hypothetical protein; KEGG: bbl:BLBBGE_302 0.0079 topA; DNA topoisomerase I K03168; Psort location: Cytoplasmic, score: 7.50. | Cell wall-binding repeat protein; KEGG: smb:smi_1563 7.5e-21 lytC; choline-binding protein LytC, 4-beta-N-acetylmuramidase, Cpb13; Psort location: Extracellular, score: 8.91. | 0.442 |
| KXB57535.1 | TopB | HMPREF3186_01720 | HMPREF3186_01633 | Hypothetical protein; KEGG: bbl:BLBBGE_302 0.0079 topA; DNA topoisomerase I K03168; Psort location: Cytoplasmic, score: 7.50. | KEGG: cbn:CbC4_2099 9.8e-186 DNA topoisomerase III; K03169 DNA topoisomerase III; Psort location: Cytoplasmic, score: 9.97. | 0.409 |
| KXB57535.1 | topA | HMPREF3186_01720 | HMPREF3186_00417 | Hypothetical protein; KEGG: bbl:BLBBGE_302 0.0079 topA; DNA topoisomerase I K03168; Psort location: Cytoplasmic, score: 7.50. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.409 |
| KXB57535.1 | uvrB | HMPREF3186_01720 | HMPREF3186_01721 | Hypothetical protein; KEGG: bbl:BLBBGE_302 0.0079 topA; DNA topoisomerase I K03168; Psort location: Cytoplasmic, score: 7.50. | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.432 |
| KXB63363.1 | KXB57535.1 | HMPREF3186_00150 | HMPREF3186_01720 | Cell wall-binding repeat protein; KEGG: smb:smi_1563 7.5e-21 lytC; choline-binding protein LytC, 4-beta-N-acetylmuramidase, Cpb13; Psort location: Extracellular, score: 8.91. | Hypothetical protein; KEGG: bbl:BLBBGE_302 0.0079 topA; DNA topoisomerase I K03168; Psort location: Cytoplasmic, score: 7.50. | 0.442 |
| TopB | KXB57535.1 | HMPREF3186_01633 | HMPREF3186_01720 | KEGG: cbn:CbC4_2099 9.8e-186 DNA topoisomerase III; K03169 DNA topoisomerase III; Psort location: Cytoplasmic, score: 9.97. | Hypothetical protein; KEGG: bbl:BLBBGE_302 0.0079 topA; DNA topoisomerase I K03168; Psort location: Cytoplasmic, score: 7.50. | 0.409 |
| TopB | topA | HMPREF3186_01633 | HMPREF3186_00417 | KEGG: cbn:CbC4_2099 9.8e-186 DNA topoisomerase III; K03169 DNA topoisomerase III; Psort location: Cytoplasmic, score: 9.97. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.503 |
| topA | KXB57535.1 | HMPREF3186_00417 | HMPREF3186_01720 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Hypothetical protein; KEGG: bbl:BLBBGE_302 0.0079 topA; DNA topoisomerase I K03168; Psort location: Cytoplasmic, score: 7.50. | 0.409 |
| topA | TopB | HMPREF3186_00417 | HMPREF3186_01633 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | KEGG: cbn:CbC4_2099 9.8e-186 DNA topoisomerase III; K03169 DNA topoisomerase III; Psort location: Cytoplasmic, score: 9.97. | 0.503 |
| uvrB | KXB57535.1 | HMPREF3186_01721 | HMPREF3186_01720 | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | Hypothetical protein; KEGG: bbl:BLBBGE_302 0.0079 topA; DNA topoisomerase I K03168; Psort location: Cytoplasmic, score: 7.50. | 0.432 |