STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
PtsIPhosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (570 aa)    
Predicted Functional Partners:
PtsH
Phosphocarrier protein HPr; KEGG: suh:SAMSHR1132_09300 6.0e-28 phosphocarrier protein HPr K11189; Psort location: Cytoplasmic, score: 10.00.
 
 0.999
Crr
KEGG: bmd:BMD_4004 3.9e-40 ptbA; sugar phosphotransferase system, glucose subfamily, IIA component; K02777 PTS system, glucose-specific IIA component; Psort location: CytoplasmicMembrane, score: 8.78.
 
 0.990
FruA
KEGG: aur:HMPREF9243_1309 1.3e-181 fruA_2; PTS system fructose-specific transporter subunit IIABC; K02768 PTS system, fructose-specific IIA component; K02769 PTS system, fructose-specific IIB component K02770; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.988
GlcB
Phosphotransferase system, EIIC; KEGG: eha:Ethha_0723 3.8e-113 PTS system glucose-like transporter subunit IIB; K02763 PTS system, D-glucosamine-specific IIA component; K02764 PTS system, D-glucosamine-specific IIB component K02765; Psort location: CytoplasmicMembrane, score: 10.00.
  
 0.842
LacC
1-phosphofructokinase; KEGG: aur:HMPREF9243_1310 1.4e-69 pfkB; 1-phosphofructokinase K00882; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.803
PtsG
PTS system maltose-specific EIICB component; KEGG: lba:Lebu_1527 7.0e-176 PTS system alpha-glucoside-specific transporter subunit IIBC; K02749 PTS system, arbutin-like IIB component K02750; Psort location: CytoplasmicMembrane, score: 10.00.
  
 0.803
ManX
Putative PTS system mannose-specific EIIAB component; KEGG: lba:Lebu_0457 2.4e-127 PTS system mannose/fructose/sorbose family transporter subunit IIA; K02793 PTS system, mannose-specific IIA component K02794; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.606
hprK
HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...]
 
   
 0.505
tuf
Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
  
    0.477
KXB62705.1
Dihydrolipoyl dehydrogenase; KEGG: sgo:SGO_1130 6.0e-186 dihydrolipoamide dehydrogenase K00382; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.470
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.