STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PheT_2tRNA binding domain protein; KEGG: efu:HMPREF0351_10247 1.9e-40 pheT; phenylalanine--tRNA ligase beta subunit K06878; Psort location: Cytoplasmic, score: 9.97; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (201 aa)    
Predicted Functional Partners:
pheS
KEGG: afl:Aflv_0542 7.6e-115 pheS; phenylalanyl-tRNA synthetase subunit alpha; K01889 phenylalanyl-tRNA synthetase alpha chain; Psort location: Cytoplasmic, score: 10.00.
 
 
 0.878
KXB57125.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.725
KXB57127.1
Hypothetical protein; KEGG: dme:Dmel_CG18255 4.4e-30 Strn-Mlck; Stretchin-Mlck K00907; Psort location: Cytoplasmic, score: 7.50.
       0.697
PurL
KEGG: ipo:Ilyop_2204 0. phosphoribosylformylglycinamidine synthase K01952; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.642
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
  
 0.620
secD
Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
  
 
 0.588
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.499
KXB59371.1
Interleukin-1 / 18; KEGG: lsn:LSA_07000 7.4e-26 hypothetical protein; K03722 ATP-dependent DNA helicase DinG; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.438
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
  
 0.411
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.408
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
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