node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
hisI | nadE | SYMBAF_20258 | SYMBAF_80078 | Fused phosphoribosyl-AMP cyclohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the PRA-CH family. | Putative glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.989 |
hisI | polA | SYMBAF_20258 | SYMBAF_110277 | Fused phosphoribosyl-AMP cyclohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the PRA-CH family. | Fused DNA polymerase I 5'->3' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.978 |
hisI | prfA | SYMBAF_20258 | SYMBAF_50250 | Fused phosphoribosyl-AMP cyclohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the PRA-CH family. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.968 |
hisI | pyrG | SYMBAF_20258 | SYMBAF_10181 | Fused phosphoribosyl-AMP cyclohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the PRA-CH family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.831 |
hisI | rho | SYMBAF_20258 | SYMBAF_160220 | Fused phosphoribosyl-AMP cyclohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the PRA-CH family. | Transcription termination factor; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.983 |
hisI | rpoA | SYMBAF_20258 | SYMBAF_110014 | Fused phosphoribosyl-AMP cyclohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the PRA-CH family. | RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.984 |
hisI | rpoZ | SYMBAF_20258 | SYMBAF_110253 | Fused phosphoribosyl-AMP cyclohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the PRA-CH family. | RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.983 |
hisI | rpsA | SYMBAF_20258 | SYMBAF_30063 | Fused phosphoribosyl-AMP cyclohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the PRA-CH family. | 30S ribosomal subunit protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.525 |
hisI | rpsD | SYMBAF_20258 | SYMBAF_110015 | Fused phosphoribosyl-AMP cyclohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the PRA-CH family. | 30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.981 |
hisI | yidC | SYMBAF_20258 | SYMBAF_140040 | Fused phosphoribosyl-AMP cyclohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the PRA-CH family. | Cytoplasmic insertase into membrane protein, Sec system; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.781 |
nadE | hisI | SYMBAF_80078 | SYMBAF_20258 | Putative glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Fused phosphoribosyl-AMP cyclohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the PRA-CH family. | 0.989 |
nadE | polA | SYMBAF_80078 | SYMBAF_110277 | Putative glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Fused DNA polymerase I 5'->3' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.986 |
nadE | prfA | SYMBAF_80078 | SYMBAF_50250 | Putative glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.994 |
nadE | pyrG | SYMBAF_80078 | SYMBAF_10181 | Putative glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.959 |
nadE | rho | SYMBAF_80078 | SYMBAF_160220 | Putative glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Transcription termination factor; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.988 |
nadE | rpoA | SYMBAF_80078 | SYMBAF_110014 | Putative glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.661 |
nadE | rpoZ | SYMBAF_80078 | SYMBAF_110253 | Putative glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.564 |
nadE | rpsA | SYMBAF_80078 | SYMBAF_30063 | Putative glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 30S ribosomal subunit protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.953 |
nadE | rpsD | SYMBAF_80078 | SYMBAF_110015 | Putative glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.909 |
nadE | yidC | SYMBAF_80078 | SYMBAF_140040 | Putative glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Cytoplasmic insertase into membrane protein, Sec system; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.899 |