STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpATryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (268 aa)    
Predicted Functional Partners:
gltB
Glutamate synthase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.999
trpG
Glutamine amidotransferase (component II) of anthranilate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.999
trpD
Anthranilate phosphoribosyl transferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
  
 0.999
trpC
Fused indole-3-glycerolphosphate synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpC family.
 
 
 0.999
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 0.999
pabA
Aminodeoxychorismate synthase, subunit II; Function of strongly homologous gene; enzyme.
 
 
 0.998
hisI
Fused phosphoribosyl-AMP cyclohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.997
trpE
Component I of anthranilate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.997
guaA
GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP.
  
 
 0.997
tyrA
Fused chorismate mutase T; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.997
Your Current Organism:
Serratia symbiotica
NCBI taxonomy Id: 138074
Other names: Candidatus Serratia symbiotica, DSM 23270, LMG 25624, LMG:25624, S. symbiotica, Serratia symbiotica Sabri et al. 2011, secondary symbiont type-R of Acyrthosiphon pisum, secondary symbiont type-R of Uroleucon caligatum, strain CWBI-2.3
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