STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ybaPConserved hypothetical protein; Homologs of previously reported genes of unknown function. (268 aa)    
Predicted Functional Partners:
copA
Copper transporter; Function of homologous gene experimentally demonstrated in an other organism; transporter.
       0.982
cysG
Fragment of putative conjugal transfer protein (part 2); Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
       0.896
rimM
16S rRNA processing protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.
  
    0.872
glyQ
Glycine tRNA synthetase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.871
glyS
Glycine tRNA synthetase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.870
amiB
Putative N-acetylmuramoyl-l-alanine amidase II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
    0.870
mutL
Methyl-directed mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
       0.869
rplY
50S ribosomal subunit protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family.
       0.866
SYMBAF_60015
Hypothetical protein; Gene remnant.
  
    0.855
priA
Primosome factor n' (replication factor Y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
       0.852
Your Current Organism:
Serratia symbiotica
NCBI taxonomy Id: 138074
Other names: Candidatus Serratia symbiotica, DSM 23270, LMG 25624, LMG:25624, S. symbiotica, Serratia symbiotica Sabri et al. 2011, secondary symbiont type-R of Acyrthosiphon pisum, secondary symbiont type-R of Uroleucon caligatum, strain CWBI-2.3
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