STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EST38906.1DNA-binding protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (66 aa)    
Predicted Functional Partners:
EST30509.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
     
 0.892
EST34012.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
  0.880
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
     
 0.573
EST38905.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.566
EST37323.1
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
     
 0.559
EST36975.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
    0.474
EST39421.1
Forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the citrate synthase family.
    
  0.438
gltA
Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the citrate synthase family.
    
  0.438
EST38901.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
     0.433
EST38894.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
    0.432
Your Current Organism:
Streptomycetaceae bacterium MP11305
NCBI taxonomy Id: 1380770
Other names: S. bacterium MP113-05, Streptomycetaceae bacterium MP113-05
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