STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EST32195.1Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (461 aa)    
Predicted Functional Partners:
EST37499.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 0.995
EST23757.1
Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 0.995
EST22684.1
Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 0.984
guaB
Inosine-5`-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 0.953
EST39525.1
Molybdenum cofactor biosynthesis protein MoaD; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.948
EST20923.1
Molybdenum cofactor biosynthesis protein MoaD; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.948
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.947
EST39678.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.932
EST37794.1
Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 0.931
EST39257.1
3-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 0.929
Your Current Organism:
Streptomycetaceae bacterium MP11305
NCBI taxonomy Id: 1380770
Other names: S. bacterium MP113-05, Streptomycetaceae bacterium MP113-05
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