STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EST23757.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (383 aa)    
Predicted Functional Partners:
EST32195.1
Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 0.995
EST39678.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.934
EST37098.1
Cysteine synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 0.919
EST20919.1
Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.916
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.901
EST34560.1
5,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the methylenetetrahydrofolate reductase family.
  
 0.893
EST30062.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 
 0.876
EST37237.1
Sulfite reductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 0.846
EST29263.1
Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.841
EST21690.1
Thiosulfate sulfurtransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 
 0.834
Your Current Organism:
Streptomycetaceae bacterium MP11305
NCBI taxonomy Id: 1380770
Other names: S. bacterium MP113-05, Streptomycetaceae bacterium MP113-05
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