STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
nfoApurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (280 aa)    
Predicted Functional Partners:
KRN55589.1
Exodeoxyribonuclease III.
    
 0.944
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
 
 0.864
KRN54960.1
Phosphopantothenoylcysteine decarboxylase phosphopantothenate cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
       0.787
KRN54959.1
Zinc ribbon domain protein.
       0.786
KRN54962.1
ABC transporter-like protein.
       0.786
KRN54963.1
ABC transporter-like protein.
       0.727
KRN54964.1
ABC transporter-like protein.
       0.727
KRN55917.1
single-stranded-DNA-specific exonuclease RecJ.
  
 
 0.666
KRN54958.1
Class V aminotransferase.
  
    0.622
KRN54957.1
Ribulose-5-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
       0.580
Your Current Organism:
Atopobium minutum
NCBI taxonomy Id: 1381
Other names: A. minutum, ATCC 33267, Bacteroides minutum, CCUG 31167, DSM 20586, LMG 9439, LMG:9439, Lactobacillus minutum (sic), Lactobacillus minutus, NCFB 2751, NCIMB 702751, VPI 9428
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