node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KRN54115.1 | KRN55570.1 | IV72_GL001551 | IV72_GL001095 | Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Hypothetical protein. | 0.916 |
KRN54115.1 | KRN55678.1 | IV72_GL001551 | IV72_GL001208 | Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 60 kDa inner membrane insertion protein. | 0.987 |
KRN54115.1 | ffh | IV72_GL001551 | IV72_GL000599 | Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.985 |
KRN54115.1 | ftsY | IV72_GL001551 | IV72_GL000600 | Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.990 |
KRN54115.1 | secA | IV72_GL001551 | IV72_GL000232 | Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.996 |
KRN54115.1 | secD | IV72_GL001551 | IV72_GL001454 | Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.996 |
KRN54115.1 | secE | IV72_GL001551 | IV72_GL001073 | Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Hypothetical protein; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.998 |
KRN54115.1 | secF | IV72_GL001551 | IV72_GL001455 | Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.996 |
KRN54115.1 | secY | IV72_GL001551 | IV72_GL001038 | Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.996 |
KRN55568.1 | KRN55570.1 | IV72_GL001093 | IV72_GL001095 | PTS system N-acetylgalactosamine-specific IIC component. | Hypothetical protein. | 0.832 |
KRN55570.1 | KRN54115.1 | IV72_GL001095 | IV72_GL001551 | Hypothetical protein. | Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.916 |
KRN55570.1 | KRN55568.1 | IV72_GL001095 | IV72_GL001093 | Hypothetical protein. | PTS system N-acetylgalactosamine-specific IIC component. | 0.832 |
KRN55570.1 | KRN55678.1 | IV72_GL001095 | IV72_GL001208 | Hypothetical protein. | 60 kDa inner membrane insertion protein. | 0.888 |
KRN55570.1 | ffh | IV72_GL001095 | IV72_GL000599 | Hypothetical protein. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.903 |
KRN55570.1 | ftsY | IV72_GL001095 | IV72_GL000600 | Hypothetical protein. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.903 |
KRN55570.1 | secA | IV72_GL001095 | IV72_GL000232 | Hypothetical protein. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.939 |
KRN55570.1 | secD | IV72_GL001095 | IV72_GL001454 | Hypothetical protein. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.979 |
KRN55570.1 | secE | IV72_GL001095 | IV72_GL001073 | Hypothetical protein. | Hypothetical protein; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.942 |
KRN55570.1 | secF | IV72_GL001095 | IV72_GL001455 | Hypothetical protein. | Export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.979 |
KRN55570.1 | secY | IV72_GL001095 | IV72_GL001038 | Hypothetical protein. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.920 |