node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KRN54985.1 | KRN55673.1 | IV72_GL000481 | IV72_GL001203 | ATPase domain-containing protein. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.991 |
KRN54985.1 | KRN55686.1 | IV72_GL000481 | IV72_GL001216 | ATPase domain-containing protein. | DNA polymerase III subunit epsilon. | 0.940 |
KRN54985.1 | KRN55917.1 | IV72_GL000481 | IV72_GL001456 | ATPase domain-containing protein. | single-stranded-DNA-specific exonuclease RecJ. | 0.945 |
KRN54985.1 | KRN56051.1 | IV72_GL000481 | IV72_GL000184 | ATPase domain-containing protein. | UvrD REP helicase. | 0.887 |
KRN54985.1 | polA | IV72_GL000481 | IV72_GL001468 | ATPase domain-containing protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.996 |
KRN54985.1 | recA | IV72_GL000481 | IV72_GL000484 | ATPase domain-containing protein. | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.878 |
KRN54985.1 | sbcD | IV72_GL000481 | IV72_GL001355 | ATPase domain-containing protein. | Exonuclease sbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.421 |
KRN54985.1 | topA | IV72_GL000481 | IV72_GL000194 | ATPase domain-containing protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.532 |
KRN55406.1 | KRN55673.1 | IV72_GL000924 | IV72_GL001203 | Binding-protein-dependent transport systems inner membrane component. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.652 |
KRN55406.1 | KRN55686.1 | IV72_GL000924 | IV72_GL001216 | Binding-protein-dependent transport systems inner membrane component. | DNA polymerase III subunit epsilon. | 0.828 |
KRN55406.1 | KRN55917.1 | IV72_GL000924 | IV72_GL001456 | Binding-protein-dependent transport systems inner membrane component. | single-stranded-DNA-specific exonuclease RecJ. | 0.975 |
KRN55406.1 | KRN56051.1 | IV72_GL000924 | IV72_GL000184 | Binding-protein-dependent transport systems inner membrane component. | UvrD REP helicase. | 0.644 |
KRN55406.1 | polA | IV72_GL000924 | IV72_GL001468 | Binding-protein-dependent transport systems inner membrane component. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.992 |
KRN55406.1 | recA | IV72_GL000924 | IV72_GL000484 | Binding-protein-dependent transport systems inner membrane component. | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.869 |
KRN55406.1 | sbcD | IV72_GL000924 | IV72_GL001355 | Binding-protein-dependent transport systems inner membrane component. | Exonuclease sbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.992 |
KRN55406.1 | topA | IV72_GL000924 | IV72_GL000194 | Binding-protein-dependent transport systems inner membrane component. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.954 |
KRN55673.1 | KRN54985.1 | IV72_GL001203 | IV72_GL000481 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATPase domain-containing protein. | 0.991 |
KRN55673.1 | KRN55406.1 | IV72_GL001203 | IV72_GL000924 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Binding-protein-dependent transport systems inner membrane component. | 0.652 |
KRN55673.1 | KRN55686.1 | IV72_GL001203 | IV72_GL001216 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III subunit epsilon. | 0.972 |
KRN55673.1 | KRN55822.1 | IV72_GL001203 | IV72_GL001356 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exonuclease SbcC. | 0.601 |