node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DSY0138 | fhs1 | DSY0138 | DSY0205 | Hypothetical protein; Similarity to COG0685 5,10-methylenetetrahydrofolate reductase. | Hypothetical protein; Similarity to COG2759 Formyltetrahydrofolate synthetase(Evalue: 0); Belongs to the formate--tetrahydrofolate ligase family. | 0.477 |
DSY0138 | fhs2 | DSY0138 | DSY0605 | Hypothetical protein; Similarity to COG0685 5,10-methylenetetrahydrofolate reductase. | Hypothetical protein; Similarity to COG2759 Formyltetrahydrofolate synthetase(Evalue: 0); Belongs to the formate--tetrahydrofolate ligase family. | 0.477 |
DSY0138 | folD1 | DSY0138 | DSY0607 | Hypothetical protein; Similarity to COG0685 5,10-methylenetetrahydrofolate reductase. | Hypothetical protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.943 |
DSY0138 | gcvT | DSY0138 | DSY2880 | Hypothetical protein; Similarity to COG0685 5,10-methylenetetrahydrofolate reductase. | Hypothetical protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.922 |
DSY0138 | glyA | DSY0138 | DSY4927 | Hypothetical protein; Similarity to COG0685 5,10-methylenetetrahydrofolate reductase. | Hypothetical protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.951 |
DSY0606 | DSY2355 | DSY0606 | DSY2355 | Hypothetical protein; Similarity to COG3404 Methenyl tetrahydrofolate cyclohydrolase(Evalue: 2E-30). | Hypothetical protein; Similarity to COG3404 Methenyl tetrahydrofolate cyclohydrolase(Evalue: 2E-35). | 0.914 |
DSY0606 | fhs1 | DSY0606 | DSY0205 | Hypothetical protein; Similarity to COG3404 Methenyl tetrahydrofolate cyclohydrolase(Evalue: 2E-30). | Hypothetical protein; Similarity to COG2759 Formyltetrahydrofolate synthetase(Evalue: 0); Belongs to the formate--tetrahydrofolate ligase family. | 0.920 |
DSY0606 | fhs2 | DSY0606 | DSY0605 | Hypothetical protein; Similarity to COG3404 Methenyl tetrahydrofolate cyclohydrolase(Evalue: 2E-30). | Hypothetical protein; Similarity to COG2759 Formyltetrahydrofolate synthetase(Evalue: 0); Belongs to the formate--tetrahydrofolate ligase family. | 0.949 |
DSY0606 | fmt | DSY0606 | DSY2693 | Hypothetical protein; Similarity to COG3404 Methenyl tetrahydrofolate cyclohydrolase(Evalue: 2E-30). | Hypothetical protein; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.909 |
DSY0606 | folD1 | DSY0606 | DSY0607 | Hypothetical protein; Similarity to COG3404 Methenyl tetrahydrofolate cyclohydrolase(Evalue: 2E-30). | Hypothetical protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.983 |
DSY0606 | gcvT | DSY0606 | DSY2880 | Hypothetical protein; Similarity to COG3404 Methenyl tetrahydrofolate cyclohydrolase(Evalue: 2E-30). | Hypothetical protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.916 |
DSY0606 | purH | DSY0606 | DSY3927 | Hypothetical protein; Similarity to COG3404 Methenyl tetrahydrofolate cyclohydrolase(Evalue: 2E-30). | Hypothetical protein; Similarity to COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)(Evalue: 1E-155). | 0.905 |
DSY0606 | purN | DSY0606 | DSY3928 | Hypothetical protein; Similarity to COG3404 Methenyl tetrahydrofolate cyclohydrolase(Evalue: 2E-30). | Hypothetical protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.906 |
DSY2355 | DSY0606 | DSY2355 | DSY0606 | Hypothetical protein; Similarity to COG3404 Methenyl tetrahydrofolate cyclohydrolase(Evalue: 2E-35). | Hypothetical protein; Similarity to COG3404 Methenyl tetrahydrofolate cyclohydrolase(Evalue: 2E-30). | 0.914 |
DSY2355 | fhs1 | DSY2355 | DSY0205 | Hypothetical protein; Similarity to COG3404 Methenyl tetrahydrofolate cyclohydrolase(Evalue: 2E-35). | Hypothetical protein; Similarity to COG2759 Formyltetrahydrofolate synthetase(Evalue: 0); Belongs to the formate--tetrahydrofolate ligase family. | 0.920 |
DSY2355 | fhs2 | DSY2355 | DSY0605 | Hypothetical protein; Similarity to COG3404 Methenyl tetrahydrofolate cyclohydrolase(Evalue: 2E-35). | Hypothetical protein; Similarity to COG2759 Formyltetrahydrofolate synthetase(Evalue: 0); Belongs to the formate--tetrahydrofolate ligase family. | 0.920 |
DSY2355 | fmt | DSY2355 | DSY2693 | Hypothetical protein; Similarity to COG3404 Methenyl tetrahydrofolate cyclohydrolase(Evalue: 2E-35). | Hypothetical protein; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.909 |
DSY2355 | folD1 | DSY2355 | DSY0607 | Hypothetical protein; Similarity to COG3404 Methenyl tetrahydrofolate cyclohydrolase(Evalue: 2E-35). | Hypothetical protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.957 |
DSY2355 | gcvT | DSY2355 | DSY2880 | Hypothetical protein; Similarity to COG3404 Methenyl tetrahydrofolate cyclohydrolase(Evalue: 2E-35). | Hypothetical protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.916 |
DSY2355 | purH | DSY2355 | DSY3927 | Hypothetical protein; Similarity to COG3404 Methenyl tetrahydrofolate cyclohydrolase(Evalue: 2E-35). | Hypothetical protein; Similarity to COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)(Evalue: 1E-155). | 0.905 |