Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
sbcDHypothetical protein; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (409 aa)    
Predicted Functional Partners:
DSY0752
Hypothetical protein; Similarity to COG0419 ATPase involved in DNA repair(Evalue: 1E-134).
 
 0.999
polA
Hypothetical protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.980
DSY0682
Hypothetical protein; Similarity to COG0514 Superfamily II DNA helicase(Evalue: 5E-52).
  
 0.938
DSY0718
Hypothetical protein; Similarity to COG0514 Superfamily II DNA helicase(Evalue: 6E-56).
  
 0.938
recA
Hypothetical protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.851
dinG
Hypothetical protein; 3'-5' exonuclease.
  
 0.768
DSY1384
Hypothetical protein; Similarity to COG0553 Superfamily II DNA/RNA helicases, SNF2 family(Evalue: 1E-127).
  
 
 0.764
DSY0713
Hypothetical protein; Similarity to COG0514 Superfamily II DNA helicase(Evalue: 1E-53).
  
 0.756
DSY1775
Hypothetical protein; Similarity to COG0514 Superfamily II DNA helicase(Evalue: 1E-172).
  
 0.731
DSY0122
Hypothetical protein; Similarity to COG0470 ATPase involved in DNA replication(Evalue: 2E-26).
  
 0.725
Your Current Organism:
Desulfitobacterium hafniense
NCBI taxonomy Id: 138119
Other names: D. hafniense Y51, Desulfitobacterium hafniense Y51, Desulfitobacterium hafniense str. Y51, Desulfitobacterium hafniense strain Y51, Desulfitobacterium sp. Y51
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