STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mutMHypothetical protein; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (273 aa)    
Predicted Functional Partners:
coaE
Hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
 
  
 0.959
polA
Hypothetical protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.940
DSY0753
Hypothetical protein; Similarity to COG0266 Formamidopyrimidine-DNA glycosylase.
  
  
 
0.928
DSY4101
Hypothetical protein; Similarity to COG0266 Formamidopyrimidine-DNA glycosylase(Evalue: 2E-34); Belongs to the FPG family.
  
  
 
0.918
dinG
Hypothetical protein; 3'-5' exonuclease.
 
  
 0.495
DSY1898
Hypothetical protein; Similarity to COG0177 Predicted EndoIII-related endonuclease(Evalue: 4E-40).
   
  
 0.484
DSY4361
Hypothetical protein; Similarity to COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains(Evalue: 6E-76).
  
  
 0.429
DSY4650
Hypothetical protein.
  
  
 0.429
DSY1229
Hypothetical protein; Similarity to COG0322 Nuclease subunit of the excinuclease complex(Evalue: 4E-39).
  
  
 0.427
uvrC
Hypothetical protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
  
  
 0.427
Your Current Organism:
Desulfitobacterium hafniense
NCBI taxonomy Id: 138119
Other names: D. hafniense Y51, Desulfitobacterium hafniense Y51, Desulfitobacterium hafniense str. Y51, Desulfitobacterium hafniense strain Y51, Desulfitobacterium sp. Y51
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.