| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DSY2754 | ribA | DSY2754 | DSY1664 | Hypothetical protein; Similarity to COG1985 Pyrimidine reductase, riboflavin biosynthesis(Evalue: 1E-60). | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.947 |
| DSY2754 | ribD | DSY2754 | DSY1662 | Hypothetical protein; Similarity to COG1985 Pyrimidine reductase, riboflavin biosynthesis(Evalue: 1E-60). | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.550 |
| DSY2754 | ribE | DSY2754 | DSY1663 | Hypothetical protein; Similarity to COG1985 Pyrimidine reductase, riboflavin biosynthesis(Evalue: 1E-60). | Similarity to COG0307 Riboflavin synthase alpha chain(Evalue: 2E-52). | 0.804 |
| DSY2754 | ribE-2 | DSY2754 | DSY1665 | Hypothetical protein; Similarity to COG1985 Pyrimidine reductase, riboflavin biosynthesis(Evalue: 1E-60). | Riboflavin synthase beta chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.543 |
| ribA | DSY2754 | DSY1664 | DSY2754 | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | Hypothetical protein; Similarity to COG1985 Pyrimidine reductase, riboflavin biosynthesis(Evalue: 1E-60). | 0.947 |
| ribA | ribD | DSY1664 | DSY1662 | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
| ribA | ribE | DSY1664 | DSY1663 | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | Similarity to COG0307 Riboflavin synthase alpha chain(Evalue: 2E-52). | 0.999 |
| ribA | ribE-2 | DSY1664 | DSY1665 | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | Riboflavin synthase beta chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.999 |
| ribA | ribF | DSY1664 | DSY2513 | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | FAD synthase; Similarity to COG0196 FAD synthase(Evalue: 2E-55); Belongs to the ribF family. | 0.757 |
| ribD | DSY2754 | DSY1662 | DSY2754 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Hypothetical protein; Similarity to COG1985 Pyrimidine reductase, riboflavin biosynthesis(Evalue: 1E-60). | 0.550 |
| ribD | ribA | DSY1662 | DSY1664 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.999 |
| ribD | ribE | DSY1662 | DSY1663 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Similarity to COG0307 Riboflavin synthase alpha chain(Evalue: 2E-52). | 0.999 |
| ribD | ribE-2 | DSY1662 | DSY1665 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin synthase beta chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.997 |
| ribD | ribF | DSY1662 | DSY2513 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | FAD synthase; Similarity to COG0196 FAD synthase(Evalue: 2E-55); Belongs to the ribF family. | 0.772 |
| ribE | DSY2754 | DSY1663 | DSY2754 | Similarity to COG0307 Riboflavin synthase alpha chain(Evalue: 2E-52). | Hypothetical protein; Similarity to COG1985 Pyrimidine reductase, riboflavin biosynthesis(Evalue: 1E-60). | 0.804 |
| ribE | ribA | DSY1663 | DSY1664 | Similarity to COG0307 Riboflavin synthase alpha chain(Evalue: 2E-52). | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.999 |
| ribE | ribD | DSY1663 | DSY1662 | Similarity to COG0307 Riboflavin synthase alpha chain(Evalue: 2E-52). | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
| ribE | ribE-2 | DSY1663 | DSY1665 | Similarity to COG0307 Riboflavin synthase alpha chain(Evalue: 2E-52). | Riboflavin synthase beta chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.999 |
| ribE | ribF | DSY1663 | DSY2513 | Similarity to COG0307 Riboflavin synthase alpha chain(Evalue: 2E-52). | FAD synthase; Similarity to COG0196 FAD synthase(Evalue: 2E-55); Belongs to the ribF family. | 0.941 |
| ribE-2 | DSY2754 | DSY1665 | DSY2754 | Riboflavin synthase beta chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | Hypothetical protein; Similarity to COG1985 Pyrimidine reductase, riboflavin biosynthesis(Evalue: 1E-60). | 0.543 |