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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ribESimilarity to COG0307 Riboflavin synthase alpha chain(Evalue: 2E-52). (214 aa)    
Predicted Functional Partners:
ribD
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
 0.999
ribA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
 
 0.999
ribE-2
Riboflavin synthase beta chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 0.999
ribF
FAD synthase; Similarity to COG0196 FAD synthase(Evalue: 2E-55); Belongs to the ribF family.
  
 
 0.944
hisI
Hypothetical protein; Similarity to COG0139 Phosphoribosyl-AMP cyclohydrolase(Evalue: 5E-29); In the N-terminal section; belongs to the PRA-CH family.
  
    0.796
DSY2754
Hypothetical protein; Similarity to COG1985 Pyrimidine reductase, riboflavin biosynthesis(Evalue: 1E-60).
  
  
 0.781
DSY0307
Hypothetical protein; Similarity to COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases(Evalue: 1E-105).
  
    0.764
DSY3900
Hypothetical protein; Similarity to COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases(Evalue: 1E-100).
  
    0.764
rpmE
50S ribosomal protein L31; Binds the 23S rRNA.
   
    0.647
secF
Hypothetical protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
     
 0.422
Your Current Organism:
Desulfitobacterium hafniense
NCBI taxonomy Id: 138119
Other names: D. hafniense Y51, Desulfitobacterium hafniense Y51, Desulfitobacterium hafniense str. Y51, Desulfitobacterium hafniense strain Y51, Desulfitobacterium sp. Y51
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