Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sucD-2Hypothetical protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (298 aa)    
Predicted Functional Partners:
DSY0245
Hypothetical protein; Similarity to COG0045 Succinyl-CoA synthetase beta subunit(Evalue: 1E-67).
 0.999
DSY0982
Hypothetical protein; Similarity to COG0045 Succinyl-CoA synthetase beta subunit(Evalue: 4E-71).
 0.999
DSY1926
Hypothetical protein; Similarity to COG0045 Succinyl-CoA synthetase beta subunit(Evalue: 9E-50).
 0.998
frdB
Similarity to COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein(Evalue: 1E-95).
 
 0.982
frdC
Similarity to COG2009 Succinate dehydrogenase/fumarate reductase cytochrome b subunit(Evalue: 2E-50).
  
 
 0.960
frdA
Similarity to COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunits(Evalue: 0).
 
 0.957
porA
Similarity to COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit(Evalue: 1E-165).
  
 0.941
porA-2
Similarity to COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit(Evalue: 1E-156).
  
 
 0.922
sucD
Hypothetical protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
  
 
0.911
DSY0246
Hypothetical protein; Similarity to COG0074 Succinyl-CoA synthetase alpha subunit(Evalue: 3E-45).
  
  
 
0.910
Your Current Organism:
Desulfitobacterium hafniense
NCBI taxonomy Id: 138119
Other names: D. hafniense Y51, Desulfitobacterium hafniense Y51, Desulfitobacterium hafniense str. Y51, Desulfitobacterium hafniense strain Y51, Desulfitobacterium sp. Y51
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