STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DSY2052Hypothetical protein; Similarity to COG0516 IMP dehydrogenase/GMP reductase(Evalue: 6E-40). (506 aa)    
Predicted Functional Partners:
guaA
Hypothetical protein; Catalyzes the synthesis of GMP from XMP.
 0.999
purA
Hypothetical protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.992
purH
Hypothetical protein; Similarity to COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)(Evalue: 1E-155).
  
 
 0.977
DSY3221
Hypothetical protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 0.951
surE
Hypothetical protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.938
DSY3939
Hypothetical protein; Similarity to COG0634 Hypoxanthine-guanine phosphoribosyltransferase(Evalue: 2E-55); Belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
 0.926
DSY3934
Hypothetical protein; Similarity to COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain(Evalue: 0).
 
  
 0.891
ribA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
  
 0.857
pheT
Hypothetical protein; Similarity to COG0072 Phenylalanyl-tRNA synthetase beta subunit(Evalue: 1E-135).
  
  
 0.838
purM
Hypothetical protein; Similarity to COG0150 Phosphoribosylaminoimidazol (AIR) synthetase(Evalue: 1E-114).
 
  
 0.831
Your Current Organism:
Desulfitobacterium hafniense
NCBI taxonomy Id: 138119
Other names: D. hafniense Y51, Desulfitobacterium hafniense Y51, Desulfitobacterium hafniense str. Y51, Desulfitobacterium hafniense strain Y51, Desulfitobacterium sp. Y51
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