node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DSY0207 | DSY0209 | DSY0207 | DSY0209 | Hypothetical protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Hypothetical protein; Similarity to COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (Evalue: 9E-37). | 0.999 |
DSY0207 | DSY3187 | DSY0207 | DSY3187 | Hypothetical protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Hypothetical protein; Similarity to COG0285 Folylpolyglutamate synthase(Evalue: 9E-79). | 0.997 |
DSY0207 | fhs1 | DSY0207 | DSY0205 | Hypothetical protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Hypothetical protein; Similarity to COG2759 Formyltetrahydrofolate synthetase(Evalue: 0); Belongs to the formate--tetrahydrofolate ligase family. | 0.576 |
DSY0207 | fhs2 | DSY0207 | DSY0605 | Hypothetical protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Hypothetical protein; Similarity to COG2759 Formyltetrahydrofolate synthetase(Evalue: 0); Belongs to the formate--tetrahydrofolate ligase family. | 0.444 |
DSY0207 | folE | DSY0207 | DSY0603 | Hypothetical protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Hypothetical protein; Similarity to COG0302 GTP cyclohydrolase I(Evalue: 4E-70). | 0.917 |
DSY0207 | folE-2 | DSY0207 | DSY1825 | Hypothetical protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Hypothetical protein; Similarity to COG0302 GTP cyclohydrolase I(Evalue: 8E-71). | 0.920 |
DSY0207 | ribD | DSY0207 | DSY1662 | Hypothetical protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.798 |
DSY0209 | DSY0207 | DSY0209 | DSY0207 | Hypothetical protein; Similarity to COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (Evalue: 9E-37). | Hypothetical protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
DSY0209 | DSY3187 | DSY0209 | DSY3187 | Hypothetical protein; Similarity to COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (Evalue: 9E-37). | Hypothetical protein; Similarity to COG0285 Folylpolyglutamate synthase(Evalue: 9E-79). | 0.941 |
DSY0209 | folE | DSY0209 | DSY0603 | Hypothetical protein; Similarity to COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (Evalue: 9E-37). | Hypothetical protein; Similarity to COG0302 GTP cyclohydrolase I(Evalue: 4E-70). | 0.979 |
DSY0209 | folE-2 | DSY0209 | DSY1825 | Hypothetical protein; Similarity to COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (Evalue: 9E-37). | Hypothetical protein; Similarity to COG0302 GTP cyclohydrolase I(Evalue: 8E-71). | 0.992 |
DSY0209 | ribD | DSY0209 | DSY1662 | Hypothetical protein; Similarity to COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (Evalue: 9E-37). | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.714 |
DSY3187 | DSY0207 | DSY3187 | DSY0207 | Hypothetical protein; Similarity to COG0285 Folylpolyglutamate synthase(Evalue: 9E-79). | Hypothetical protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.997 |
DSY3187 | DSY0209 | DSY3187 | DSY0209 | Hypothetical protein; Similarity to COG0285 Folylpolyglutamate synthase(Evalue: 9E-79). | Hypothetical protein; Similarity to COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (Evalue: 9E-37). | 0.941 |
DSY3187 | fhs1 | DSY3187 | DSY0205 | Hypothetical protein; Similarity to COG0285 Folylpolyglutamate synthase(Evalue: 9E-79). | Hypothetical protein; Similarity to COG2759 Formyltetrahydrofolate synthetase(Evalue: 0); Belongs to the formate--tetrahydrofolate ligase family. | 0.629 |
DSY3187 | fhs2 | DSY3187 | DSY0605 | Hypothetical protein; Similarity to COG0285 Folylpolyglutamate synthase(Evalue: 9E-79). | Hypothetical protein; Similarity to COG2759 Formyltetrahydrofolate synthetase(Evalue: 0); Belongs to the formate--tetrahydrofolate ligase family. | 0.629 |
DSY3187 | folE | DSY3187 | DSY0603 | Hypothetical protein; Similarity to COG0285 Folylpolyglutamate synthase(Evalue: 9E-79). | Hypothetical protein; Similarity to COG0302 GTP cyclohydrolase I(Evalue: 4E-70). | 0.617 |
DSY3187 | folE-2 | DSY3187 | DSY1825 | Hypothetical protein; Similarity to COG0285 Folylpolyglutamate synthase(Evalue: 9E-79). | Hypothetical protein; Similarity to COG0302 GTP cyclohydrolase I(Evalue: 8E-71). | 0.617 |
DSY3187 | glyA | DSY3187 | DSY4927 | Hypothetical protein; Similarity to COG0285 Folylpolyglutamate synthase(Evalue: 9E-79). | Hypothetical protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.703 |
DSY3187 | guaA | DSY3187 | DSY3938 | Hypothetical protein; Similarity to COG0285 Folylpolyglutamate synthase(Evalue: 9E-79). | Hypothetical protein; Catalyzes the synthesis of GMP from XMP. | 0.791 |