STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobB-2Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (491 aa)    
Predicted Functional Partners:
cobH
Similarity to COG2082 Precorrin isomerase(Evalue: 8E-36).
 
 0.992
DSY4057
Hypothetical protein; Similarity to COG0079 Histidinol-phosphate aminotransferase/Tyrosine aminotransferase(Evalue: 2E-44).
  
 0.990
cobA-4
Similarity to COG2109 ATP:corrinoid adenosyltransferase(Evalue: 2E-26).
 
 
 0.982
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
  
 0.971
cbiD
cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.965
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.964
cobN
Similarity to COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases(Evalue: 1E-161).
 
 
 0.955
cobA-2
Similarity to COG2109 ATP:corrinoid adenosyltransferase(Evalue: 1E-40).
 
 0.928
cobA-3
Similarity to COG2109 ATP:corrinoid adenosyltransferase(Evalue: 1E-31).
 
 
 0.928
cobA
Similarity to COG2109 ATP:corrinoid adenosyltransferase(Evalue: 7E-36).
 
 
 0.923
Your Current Organism:
Desulfitobacterium hafniense
NCBI taxonomy Id: 138119
Other names: D. hafniense Y51, Desulfitobacterium hafniense Y51, Desulfitobacterium hafniense str. Y51, Desulfitobacterium hafniense strain Y51, Desulfitobacterium sp. Y51
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