STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DSY4240Hypothetical protein; Similarity to COG0789 Predicted transcriptional regulators(Evalue: 9E-43). (254 aa)    
Predicted Functional Partners:
DSY4241
Hypothetical protein; Similarity to COG0546 Predicted phosphatases.
       0.547
DSY4242
Hypothetical protein; Similarity to COG2008 Threonine aldolase(Evalue: 9E-44).
       0.539
DSY1417
Hypothetical protein; Similarity to COG2214 Molecular chaperones, DnaJ class(Evalue: 6E-55).
  
 
 0.483
DSY1645
Hypothetical protein.
  
 
 0.483
dnaJ
Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, Dna [...]
  
 
 0.483
DSY4328
Hypothetical protein; Similarity to COG0174 Glutamine synthase(Evalue: 1E-140); Belongs to the glutamine synthetase family.
  
 
 0.451
DSY0460
Hypothetical protein; Similarity to COG0642 Signal transduction histidine kinase(Evalue: 1E-53).
 
 
 
 0.430
DSY3378
Hypothetical protein; Similarity to COG0642 Signal transduction histidine kinase(Evalue: 1E-61).
   
 
 0.419
DSY4243
Hypothetical protein; Similarity to COG2135 Uncharacterized ACR(Evalue: 1E-58); Belongs to the SOS response-associated peptidase family.
       0.412
sigA
Hypothetical protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.410
Your Current Organism:
Desulfitobacterium hafniense
NCBI taxonomy Id: 138119
Other names: D. hafniense Y51, Desulfitobacterium hafniense Y51, Desulfitobacterium hafniense str. Y51, Desulfitobacterium hafniense strain Y51, Desulfitobacterium sp. Y51
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.