KJD34546.1 protein (Tamlana nanhaiensis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

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[Homology]

Score

KJD34546.1

Exopolygalacturonase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 28 family. (448 aa)

Predicted Functional Partners:

KJD34747.1

0.853

KJD34745.1

0.849

KJD31089.1

0.829

KJD34547.1

0.792

KJD31101.1

0.791

KJD34755.1

0.744

KJD31113.1

0.743

KJD34831.1

0.703

KJD31092.1

0.677

KJD34838.1

0.583

Your Current Organism:

Tamlana nanhaiensis

NCBI taxonomy Id: 1382798
Other names: CGMCC 1.12469, LMG 27420, LMG:27420, MCCC 1A06648, T. nanhaiensis, Tamlana sp. FHC16, strain FHC16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KJD31089.1	KJD31092.1	PK35_16545	PK35_16575	Rhamnogalacturonan acetylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pectin methylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.988
KJD31089.1	KJD31113.1	PK35_16545	PK35_16590	Rhamnogalacturonan acetylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycosyl hydrolase family 88; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.820
KJD31089.1	KJD34546.1	PK35_16545	PK35_01805	Rhamnogalacturonan acetylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Exopolygalacturonase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 28 family.	0.829
KJD31089.1	KJD34755.1	PK35_16545	PK35_03170	Rhamnogalacturonan acetylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycoside hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.738
KJD31089.1	KJD34838.1	PK35_16545	PK35_03150	Rhamnogalacturonan acetylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Starch-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.417
KJD31092.1	KJD31089.1	PK35_16575	PK35_16545	Pectin methylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Rhamnogalacturonan acetylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.988
KJD31092.1	KJD31101.1	PK35_16575	PK35_16635	Pectin methylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.981
KJD31092.1	KJD31113.1	PK35_16575	PK35_16590	Pectin methylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycosyl hydrolase family 88; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.837
KJD31092.1	KJD34546.1	PK35_16575	PK35_01805	Pectin methylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Exopolygalacturonase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 28 family.	0.677
KJD31092.1	KJD34745.1	PK35_16575	PK35_03075	Pectin methylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Rhamnogalacturonan acetylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
KJD31092.1	KJD34747.1	PK35_16575	PK35_03085	Pectin methylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Rhamnogalacturonan acetylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.789
KJD31092.1	KJD34755.1	PK35_16575	PK35_03170	Pectin methylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycoside hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.604
KJD31101.1	KJD31092.1	PK35_16635	PK35_16575	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pectin methylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.981
KJD31101.1	KJD31113.1	PK35_16635	PK35_16590	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycosyl hydrolase family 88; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.812
KJD31101.1	KJD34546.1	PK35_16635	PK35_01805	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Exopolygalacturonase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 28 family.	0.791
KJD31101.1	KJD34755.1	PK35_16635	PK35_03170	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycoside hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.727
KJD31113.1	KJD31089.1	PK35_16590	PK35_16545	Glycosyl hydrolase family 88; Derived by automated computational analysis using gene prediction method: Protein Homology.	Rhamnogalacturonan acetylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.820
KJD31113.1	KJD31092.1	PK35_16590	PK35_16575	Glycosyl hydrolase family 88; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pectin methylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.837
KJD31113.1	KJD31101.1	PK35_16590	PK35_16635	Glycosyl hydrolase family 88; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.812
KJD31113.1	KJD34546.1	PK35_16590	PK35_01805	Glycosyl hydrolase family 88; Derived by automated computational analysis using gene prediction method: Protein Homology.	Exopolygalacturonase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 28 family.	0.743

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Network Stats

number of nodes:

11

number of edges:

37

average node degree:

6.73

avg. local clustering coefficient:

0.701

expected number of edges:

10

PPI enrichment p-value:

7.98e-11

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006352

DNA-templated transcription, initiation

11 of 24

2.26

8.41

1.92e-21

GO:0050896

Response to stimulus

11 of 334

1.11

1.61

2.89e-11

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016987

Sigma factor activity

11 of 24

2.26

8.48

1.09e-21

GO:0003677

DNA binding

11 of 369

1.07

1.45

3.36e-10

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

11 of 1196

0.56

0.49

8.24e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:6080

RNA polymerase sigma-70 like, and Sigma factor antagonist activity

10 of 35

2.05

6.17

5.00e-17

CL:6082

RNA polymerase sigma-70 like, and Sigma factor antagonist activity

8 of 28

2.05

5.1

3.69e-13

CL:6084

RNA polymerase sigma-70 like, and FecR protein

7 of 22

2.1

4.7

1.65e-11

CL:6109

Sigma-70, region 4

4 of 6

2.42

3.18

7.33e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02020

Two-component system

11 of 478

0.96

1.16

4.17e-09

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0000428

DNA-directed RNA polymerase complex

11 of 55

1.9

5.74

1.17e-18

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0731

Sigma factor

11 of 22

2.3

8.94

1.53e-22

KW-0238

DNA-binding

11 of 178

1.39

2.67

4.04e-14

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF04542

Sigma-70 region 2

10 of 19

2.32

8.05

2.09e-19

PF08281

Sigma-70, region 4

8 of 13

2.39

6.76

3.32e-15

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR007627

RNA polymerase sigma-70 region 2

11 of 20

2.34

9.0

4.97e-22

IPR039425

RNA polymerase sigma-70 like

11 of 21

2.32

8.89

4.97e-22

IPR014284

RNA polymerase sigma-70 like domain

11 of 22

2.3

8.78

4.97e-22

IPR013325

RNA polymerase sigma factor, region 2

11 of 22

2.3

8.78

4.97e-22

IPR013324

RNA polymerase sigma factor, region 3/4-like

11 of 22

2.3

8.78

4.97e-22

(more ...)

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