| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KRO01762.1 | KRO01866.1 | IV60_GL001000 | IV60_GL001112 | Inosine-5-monophosphate dehydrogenase. | Phosphoribosylformylglycinamidine synthase. | 0.876 |
| KRO01762.1 | guaA | IV60_GL001000 | IV60_GL001453 | Inosine-5-monophosphate dehydrogenase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.999 |
| KRO01762.1 | murI | IV60_GL001000 | IV60_GL001091 | Inosine-5-monophosphate dehydrogenase. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.517 |
| KRO01762.1 | rdgB | IV60_GL001000 | IV60_GL000979 | Inosine-5-monophosphate dehydrogenase. | Non-canonical purine NTP pyrophosphatase, RdgB HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.943 |
| KRO01848.1 | murI | IV60_GL001092 | IV60_GL001091 | Fkbp-type peptidyl-prolyl cis-trans isomerase. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.525 |
| KRO01866.1 | KRO01762.1 | IV60_GL001112 | IV60_GL001000 | Phosphoribosylformylglycinamidine synthase. | Inosine-5-monophosphate dehydrogenase. | 0.876 |
| KRO01866.1 | KRO03079.1 | IV60_GL001112 | IV60_GL000257 | Phosphoribosylformylglycinamidine synthase. | NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.903 |
| KRO01866.1 | alr | IV60_GL001112 | IV60_GL000890 | Phosphoribosylformylglycinamidine synthase. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.484 |
| KRO01866.1 | guaA | IV60_GL001112 | IV60_GL001453 | Phosphoribosylformylglycinamidine synthase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.985 |
| KRO01866.1 | murD | IV60_GL001112 | IV60_GL000183 | Phosphoribosylformylglycinamidine synthase. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.874 |
| KRO01866.1 | murI | IV60_GL001112 | IV60_GL001091 | Phosphoribosylformylglycinamidine synthase. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.880 |
| KRO03079.1 | KRO01866.1 | IV60_GL000257 | IV60_GL001112 | NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Phosphoribosylformylglycinamidine synthase. | 0.903 |
| KRO03079.1 | murI | IV60_GL000257 | IV60_GL001091 | NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.820 |
| alr | KRO01866.1 | IV60_GL000890 | IV60_GL001112 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Phosphoribosylformylglycinamidine synthase. | 0.484 |
| alr | guaA | IV60_GL000890 | IV60_GL001453 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.487 |
| alr | murD | IV60_GL000890 | IV60_GL000183 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.710 |
| alr | murF | IV60_GL000890 | IV60_GL000181 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.979 |
| alr | murG | IV60_GL000890 | IV60_GL000185 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Glycosyltransferase, family 28; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.485 |
| alr | murI | IV60_GL000890 | IV60_GL001091 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.686 |
| guaA | KRO01762.1 | IV60_GL001453 | IV60_GL001000 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Inosine-5-monophosphate dehydrogenase. | 0.999 |