KJB94669.1 protein (Skermanella aerolata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

KJB94669.1

ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (352 aa)

Predicted Functional Partners:

KJB94670.1

0.991

KJB94671.1

0.979

KJB97045.1

0.969

KJB97047.1

0.969

KJB93476.1

0.936

KJB97423.1

0.935

KJB94404.1

0.935

KJB93319.1

0.934

KJB92504.1

0.934

KJB94358.1

0.933

Your Current Organism:

Skermanella aerolata

NCBI taxonomy Id: 1385368
Other names: S. aerolata KACC 11604, Skermanella aerolata 5416T-32, Skermanella aerolata DSM 18479, Skermanella aerolata KACC 11604

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KJB92504.1	KJB93319.1	N826_22280	N826_18070	Nitrate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.481
KJB92504.1	KJB93476.1	N826_22280	N826_17665	Nitrate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.491
KJB92504.1	KJB94358.1	N826_22280	N826_11340	Nitrate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Taurine ABC transporter permease; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.537
KJB92504.1	KJB94669.1	N826_22280	N826_09135	Nitrate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.934
KJB92504.1	KJB94671.1	N826_22280	N826_09145	Nitrate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Nitrate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.953
KJB92504.1	KJB97045.1	N826_22280	N826_29270	Nitrate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.838
KJB92504.1	KJB97047.1	N826_22280	N826_29280	Nitrate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.551
KJB92504.1	KJB97423.1	N826_22280	N826_01255	Nitrate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.818
KJB93319.1	KJB92504.1	N826_18070	N826_22280	ABC transporter permease; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Nitrate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.481
KJB93319.1	KJB94358.1	N826_18070	N826_11340	ABC transporter permease; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Taurine ABC transporter permease; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.718
KJB93319.1	KJB94669.1	N826_18070	N826_09135	ABC transporter permease; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.934
KJB93319.1	KJB94670.1	N826_18070	N826_09140	ABC transporter permease; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.518
KJB93319.1	KJB94671.1	N826_18070	N826_09145	ABC transporter permease; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Nitrate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.913
KJB93319.1	KJB97045.1	N826_18070	N826_29270	ABC transporter permease; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.715
KJB93319.1	KJB97047.1	N826_18070	N826_29280	ABC transporter permease; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.894
KJB93476.1	KJB92504.1	N826_17665	N826_22280	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Nitrate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.491
KJB93476.1	KJB94358.1	N826_17665	N826_11340	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Taurine ABC transporter permease; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.738
KJB93476.1	KJB94669.1	N826_17665	N826_09135	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.936
KJB93476.1	KJB94670.1	N826_17665	N826_09140	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.502
KJB93476.1	KJB94671.1	N826_17665	N826_09145	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Nitrate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.955

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Network Stats

number of nodes:

11

number of edges:

54

average node degree:

9.82

avg. local clustering coefficient:

0.982

expected number of edges:

15

PPI enrichment p-value:

4.66e-15

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006166

Purine ribonucleoside salvage

2 of 4

2.65

1.0

0.0155

GO:0055086

Nucleobase-containing small molecule metabolic process

5 of 210

1.32

0.89

0.0074

GO:0072522

Purine-containing compound biosynthetic process

3 of 68

1.59

0.85

0.0182

GO:0009168

Purine ribonucleoside monophosphate biosynthetic process

2 of 17

2.02

0.83

0.0280

GO:1901137

Carbohydrate derivative biosynthetic process

4 of 222

1.2

0.72

0.0182

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:13127

Metabolism of nucleotides, and Purine nucleoside catabolic process

7 of 78

1.9

3.59

1.73e-09

CL:13128

Nucleoside monophosphate metabolic process, and Nucleoside-triphosphate diphosphatase activity

5 of 48

1.96

2.75

1.06e-06

CL:13129

Purine ribonucleoside monophosphate biosynthesis, and Adenosine deaminase domain

3 of 24

2.04

1.47

0.0014

CL:13239

Cytidine and deoxycytidylate deaminase zinc-binding region, and Bacterial bifunctional deaminase-reductase, C-terminal

2 of 5

2.55

1.13

0.0088

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00230

Purine metabolism

3 of 98

1.43

0.75

0.0250

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00383

Cytidine and deoxycytidylate deaminase zinc-binding region

2 of 7

2.4

0.76

0.0416

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