KJB89881.1 protein (Skermanella aerolata) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

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[Homology]

Score

KJB89881.1

Transposase ISRSO1; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (254 aa)

Predicted Functional Partners:

KJB89816.1

0.775

KJB90687.1

0.775

KJB90529.1

0.774

KJB89794.1

0.773

KJB89820.1

0.724

KJB95857.1

0.599

KJB91229.1

0.585

KJB95855.1

0.579

KJB89915.1

0.504

KJB89829.1

0.461

Your Current Organism:

Skermanella aerolata

NCBI taxonomy Id: 1385368
Other names: S. aerolata KACC 11604, Skermanella aerolata 5416T-32, Skermanella aerolata DSM 18479, Skermanella aerolata KACC 11604

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KJB89794.1	KJB89820.1	N826_14585	N826_16350	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Transposase IS4; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.515
KJB89794.1	KJB89829.1	N826_14585	N826_15575	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.487
KJB89794.1	KJB89881.1	N826_14585	N826_09820	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Transposase ISRSO1; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.773
KJB89794.1	KJB89915.1	N826_14585	N826_07590	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.409
KJB89794.1	KJB90529.1	N826_14585	N826_38990	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.778
KJB89794.1	KJB91229.1	N826_14585	N826_31320	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.493
KJB89794.1	KJB95855.1	N826_14585	N826_39455	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.541
KJB89794.1	KJB95857.1	N826_14585	N826_39465	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.461
KJB89816.1	KJB89820.1	N826_17040	N826_16350	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Transposase IS4; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.668
KJB89816.1	KJB89829.1	N826_17040	N826_15575	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.501
KJB89816.1	KJB89881.1	N826_17040	N826_09820	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Transposase ISRSO1; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.775
KJB89816.1	KJB89915.1	N826_17040	N826_07590	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.594
KJB89816.1	KJB91229.1	N826_17040	N826_31320	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.627
KJB89816.1	KJB95855.1	N826_17040	N826_39455	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.572
KJB89816.1	KJB95857.1	N826_17040	N826_39465	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.544
KJB89820.1	KJB89794.1	N826_16350	N826_14585	Transposase IS4; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.515
KJB89820.1	KJB89816.1	N826_16350	N826_17040	Transposase IS4; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.668
KJB89820.1	KJB89881.1	N826_16350	N826_09820	Transposase IS4; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Transposase ISRSO1; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.724
KJB89820.1	KJB90529.1	N826_16350	N826_38990	Transposase IS4; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.485
KJB89820.1	KJB90687.1	N826_16350	N826_36480	Transposase IS4; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.583

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Network Stats

number of nodes:

3

number of edges:

2

average node degree:

1.33

avg. local clustering coefficient:

0.667

expected number of edges:

2

PPI enrichment p-value:

0.527

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0048284

Organelle fusion

9 of 42

2.12

5.88

5.82e-15

GO:0007033

Vacuole organization

7 of 39

2.05

4.21

1.96e-10

GO:0016050

Vesicle organization

7 of 47

1.96

3.92

4.31e-10

GO:0034058

Endosomal vesicle fusion

4 of 4

2.79

3.84

7.14e-08

GO:0006906

Vesicle fusion

5 of 26

2.08

3.25

1.13e-07

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030897

HOPS complex

6 of 6

2.79

6.12

2.31e-12

GO:0099023

Vesicle tethering complex

7 of 42

2.01

4.33

5.16e-11

GO:0033263

CORVET complex

4 of 4

2.79

4.06

2.76e-08

GO:0005768

Endosome

9 of 114

1.69

3.63

3.04e-12

GO:0005770

Late endosome

4 of 30

1.92

2.31

1.14e-05

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:5225

HOPS complex, and Endosomal vesicle fusion

9 of 11

2.7

9.41

1.20e-19

CL:5223

RAB geranylgeranylation, and HOPS complex

10 of 31

2.3

8.06

1.20e-19

CL:5130

Mixed, incl. Vesicle tethering complex, and Membrane fusion

11 of 90

1.88

5.63

1.23e-18

CL:5227

HOPS complex

5 of 5

2.79

5.26

1.19e-10

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04138

Autophagy - yeast

7 of 78

1.74

3.23

1.63e-09

map04145

Phagosome

3 of 52

1.55

1.04

0.0055

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-5663205

Infectious disease

5 of 31

2.0

2.76

1.24e-06

MAP-1643685

Disease

5 of 40

1.89

2.56

2.00e-06

MAP-8873719

RAB geranylgeranylation

3 of 16

2.06

1.57

0.00089

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0030897

HOPS complex

7 of 8

2.73

7.13

1.40e-14

GOCC:0042597

Periplasmic space

2 of 5

2.39

1.11

0.0089

GOCC:0016020

Membrane

8 of 964

0.71

0.53

0.0041

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000547

Clathrin, heavy chain/VPS, 7-fold repeat

4 of 5

2.69

3.22

9.97e-07

IPR045111

Vacuolar protein sorting-associated protein Vps41/Vps8

2 of 2

2.79

1.0

0.0153

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00175

Rab subfamily of small GTPases

2 of 10

2.09

0.9

0.0205

SM00184

Ring finger

3 of 50

1.57

0.84

0.0186

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