node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SMC43918.1 | SMC50795.1 | SAMN06295998_101281 | SAMN06295998_10290 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase). | 0.838 |
SMC43918.1 | SMC50806.1 | SAMN06295998_101281 | SAMN06295998_10291 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.842 |
SMC43918.1 | SMC89191.1 | SAMN06295998_101281 | SAMN06295998_10999 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.817 |
SMC43918.1 | kdsA | SAMN06295998_101281 | SAMN06295998_10289 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); Belongs to the KdsA family. | 0.846 |
SMC43918.1 | lpxA | SAMN06295998_101281 | SAMN06295998_101279 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.998 |
SMC43918.1 | lpxK | SAMN06295998_101281 | SAMN06295998_102177 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.983 |
SMC45778.1 | SMC50806.1 | SAMN06295998_101428 | SAMN06295998_10291 | CBS domain-containing protein. | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.834 |
SMC45778.1 | guaA | SAMN06295998_101428 | SAMN06295998_104244 | CBS domain-containing protein. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.962 |
SMC45778.1 | guaB | SAMN06295998_101428 | SAMN06295998_101110 | CBS domain-containing protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.904 |
SMC45778.1 | kdsA | SAMN06295998_101428 | SAMN06295998_10289 | CBS domain-containing protein. | 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); Belongs to the KdsA family. | 0.601 |
SMC50795.1 | SMC43918.1 | SAMN06295998_10290 | SAMN06295998_101281 | 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase). | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.838 |
SMC50795.1 | SMC50806.1 | SAMN06295998_10290 | SAMN06295998_10291 | 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase). | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.974 |
SMC50795.1 | SMC89191.1 | SAMN06295998_10290 | SAMN06295998_10999 | 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase). | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.949 |
SMC50795.1 | kdsA | SAMN06295998_10290 | SAMN06295998_10289 | 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase). | 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); Belongs to the KdsA family. | 0.987 |
SMC50795.1 | lpxA | SAMN06295998_10290 | SAMN06295998_101279 | 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase). | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.839 |
SMC50795.1 | lpxK | SAMN06295998_10290 | SAMN06295998_102177 | 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase). | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.915 |
SMC50806.1 | SMC43918.1 | SAMN06295998_10291 | SAMN06295998_101281 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.842 |
SMC50806.1 | SMC45778.1 | SAMN06295998_10291 | SAMN06295998_101428 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | CBS domain-containing protein. | 0.834 |
SMC50806.1 | SMC50795.1 | SAMN06295998_10291 | SAMN06295998_10290 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase). | 0.974 |
SMC50806.1 | SMC53696.1 | SAMN06295998_10291 | SAMN06295998_102270 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | 0.853 |