L-lactate dehydrogenase; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:P00345; Belongs to the LDH/MDH superfamily.

Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

Succinyl-CoA ligase [ADP-forming] subunit alpha; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:P9WGC7.

Pyruvate kinase; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:Q02499; Belongs to the pyruvate kinase family.

Citrate synthase 1; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:P9WPD5; Belongs to the citrate synthase family.

Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.

Acetyl-coenzyme A synthetase; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:Q8ZKF6.

DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]