STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glmSGlutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (613 aa)    
Predicted Functional Partners:
gltB
Ferredoxin-dependent glutamate synthase 1; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:P55037.
   
 0.959
glnA_1
Glutamine synthetase; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:P77961.
  
 
 0.938
pgi
Glucose-6-phosphate isomerase; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:P0A6T1; Belongs to the GPI family.
  
 
 0.927
purL_2
Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...]
    
 0.926
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
0.925
gltD
Ab initio prediction:Prodigal:2.6; protein motif:HAMAP:MF_00994.
    
 0.923
nagA_3
N-acetylglucosamine-6-phosphate deacetylase; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:O34450.
    
 0.922
manA
Mannose-6-phosphate isomerase ManA; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:O31646.
  
 
 0.919
carA
Carbamoyl-phosphate synthase small chain; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:P0A6F1; Belongs to the CarA family.
    
 0.919
nagB_1
Glucosamine-6-phosphate deaminase; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:P59686.
  
 
 0.911
Your Current Organism:
Paludisphaera borealis
NCBI taxonomy Id: 1387353
Other names: DSM 28747, Isosphaera sp. PX4, P. borealis, Paludisphaera borealis Kulichevskaya et al. 2016, Planctomycetaceae bacterium PT1, VKM B-2904, strain PX4
Server load: low (14%) [HD]