STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
htrA_2Putative serine protease HtrA; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:P73354. (524 aa)    
Predicted Functional Partners:
trpGD
Bifunctional protein TrpGD; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
       0.773
ftsH3_2
ATP-dependent zinc metalloprotease FtsH 3; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:P72991.
    
 0.714
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
   
 0.517
zraS_11
Sensor protein ZraS; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:P14377.
 
  
 0.449
rsfS
Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
   0.448
yjoB
Putative ATPase YjoB; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:O34703; Belongs to the AAA ATPase family.
    
 0.448
phoR_4
Alkaline phosphatase synthesis sensor protein PhoR; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:P23545.
  
  
 0.430
mip
Peptidyl-prolyl cis-trans isomerase Mip; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:P51752.
  
 
 0.423
paaZ
Bifunctional protein PaaZ; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:P77455.
    
  0.418
fbp
FK506-binding protein; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:P0A0W2.
  
 
 0.416
Your Current Organism:
Paludisphaera borealis
NCBI taxonomy Id: 1387353
Other names: DSM 28747, Isosphaera sp. PX4, P. borealis, Paludisphaera borealis Kulichevskaya et al. 2016, Planctomycetaceae bacterium PT1, VKM B-2904, strain PX4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.