STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pheAP-protein; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:P0A9J8. (390 aa)    
Predicted Functional Partners:
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.989
tyrA
Prephenate dehydrogenase; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:O69721.
 0.980
hisC_2
Histidinol-phosphate aminotransferase; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:Q39YP6; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
 
 
 0.957
trpE
Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
 
 
 0.951
APW63497.1
Aspartate aminotransferase; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:P23034.
 
 
 0.941
aspC
Aspartate aminotransferase; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:Q56232.
 
 
 0.935
pabA
Aminodeoxychorismate/anthranilate synthase component 2; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:P28819.
 
 
 0.925
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
  
 0.921
aroF_1
Phospho-2-dehydro-3-deoxyheptonate aldolase; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:Q9WYH8.
 
  
 0.920
flgI
Flagellar P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
    
   0.917
Your Current Organism:
Paludisphaera borealis
NCBI taxonomy Id: 1387353
Other names: DSM 28747, Isosphaera sp. PX4, P. borealis, Paludisphaera borealis Kulichevskaya et al. 2016, Planctomycetaceae bacterium PT1, VKM B-2904, strain PX4
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