STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xerC_3Tyrosine recombinase XerC; Ab initio prediction:Prodigal:2.6; protein motif:HAMAP:MF_01808. (525 aa)    
Predicted Functional Partners:
APW63249.1
Hypothetical protein; Ab initio prediction:Prodigal:2.6.
  
  
 0.582
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.471
pyrE_2
Orotate phosphoribosyltransferase; Ab initio prediction:Prodigal:2.6; protein motif:HAMAP:MF_01208.
   
    0.471
tyrA
Prephenate dehydrogenase; Ab initio prediction:Prodigal:2.6; similar to AA sequence:UniProtKB:O69721.
  
    0.435
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.415
Your Current Organism:
Paludisphaera borealis
NCBI taxonomy Id: 1387353
Other names: DSM 28747, Isosphaera sp. PX4, P. borealis, Paludisphaera borealis Kulichevskaya et al. 2016, Planctomycetaceae bacterium PT1, VKM B-2904, strain PX4
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