STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
A0A017SJC8Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (483 aa)    
Predicted Functional Partners:
A0A017SG89
Dihydropteroate synthase.
 
 
 0.972
A0A017SDH7
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
  
  
 
0.886
A0A017S942
Phosphopantothenoylcysteine decarboxylase.
     
 0.872
A0A017SLP2
FolC bifunctional protein.
  
  
 
0.871
A0A017SMQ8
Tetrahydrobiopterin biosynthesis enzymes-like protein.
  
 
 0.835
A0A017S3S7
Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.
     
 0.825
A0A017SGU5
FSH1-domain-containing protein.
     
 0.825
A0A017SQM6
Putative C1 tetrahydrofolate synthase.
  
 
 0.817
A0A017S483
NAD(P)-binding protein.
    
 0.803
A0A017SK47
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 0.784
Your Current Organism:
Aspergillus ruber
NCBI taxonomy Id: 1388766
Other names: A. ruber CBS 135680, Aspergillus ruber CBS 135680, Aspergillus rubrum CBS 135680, Eurotium rubrum CBS 135680
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.