STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKJ08_0222Menaquinone via futalosine polyprenyltransferase; Belongs to the UbiA prenyltransferase family. (283 aa)    
Predicted Functional Partners:
ubiX
UbiX family decarboxylase associated with menaquinone via futalosine; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
 
  
 0.992
AKJ08_0811
3-polyprenyl-4-hydroxybenzoate carboxy-lyase; Belongs to the UbiD family.
 
  
 0.986
mqnA
Menaquinone via futalosine step 3; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnA subfamily.
 
   
 0.953
AKJ08_0215
Octaprenyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
 
 
 0.946
mqnD
Menaquinone via futalosine step 4; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.
 
   
 0.938
mqnE
Hypothetical protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.
 
   
 0.909
AKJ08_0221
S-adenosylhomocysteine deaminase.
 
     0.903
AKJ08_2653
Putative 4-hydroxybenzoyl CoA thioesterase.
     
 0.902
AKJ08_0223
2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I beta.
       0.773
ubiE
2-heptaprenyl-1,4-naphthoquinone methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
 
   
 0.650
Your Current Organism:
Vulgatibacter incomptus
NCBI taxonomy Id: 1391653
Other names: Cystobacteraceae bacterium B00001, DSM 27710, NBRC 109945, V. incomptus, Vulgatibacter incomptus Yamamoto et al. 2014, strain B00001
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