AKU95518.1 protein (Labilithrix luteola) - STRING interaction network

Nodes:

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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protein homology

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AKU95518.1

RNA polymerase sigma-54 factor RpoN; Belongs to the sigma-70 factor family. ECF subfamily. (195 aa)

Predicted Functional Partners:

AKU95517.1

0.773

AKU95519.1

0.533

AKU96572.1

0.474

AKV04369.1

0.453

AKV00444.1

0.408

AKU98773.1

0.407

Your Current Organism:

Labilithrix luteola

NCBI taxonomy Id: 1391654
Other names: DSM 27648, L. luteola, Labilithrix luteola Yamamoto et al. 2014, NBRC 109946, Sorangiineae bacterium B00002, strain B00002

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKU95517.1	AKU95518.1	AKJ09_02181	AKJ09_02182	Hypothetical protein.	RNA polymerase sigma-54 factor RpoN; Belongs to the sigma-70 factor family. ECF subfamily.	0.773
AKU95517.1	AKU95519.1	AKJ09_02181	AKJ09_02183	Hypothetical protein.	Putative signal peptide protein.	0.533
AKU95518.1	AKU95517.1	AKJ09_02182	AKJ09_02181	RNA polymerase sigma-54 factor RpoN; Belongs to the sigma-70 factor family. ECF subfamily.	Hypothetical protein.	0.773
AKU95518.1	AKU95519.1	AKJ09_02182	AKJ09_02183	RNA polymerase sigma-54 factor RpoN; Belongs to the sigma-70 factor family. ECF subfamily.	Putative signal peptide protein.	0.533
AKU95518.1	AKU96572.1	AKJ09_02182	AKJ09_03236	RNA polymerase sigma-54 factor RpoN; Belongs to the sigma-70 factor family. ECF subfamily.	RNA polymerase sigma factor RpoE; Belongs to the sigma-70 factor family. ECF subfamily.	0.474
AKU95518.1	AKU98773.1	AKJ09_02182	AKJ09_05437	RNA polymerase sigma-54 factor RpoN; Belongs to the sigma-70 factor family. ECF subfamily.	RNA polymerase sigma factor RpoE; Belongs to the sigma-70 factor family. ECF subfamily.	0.407
AKU95518.1	AKV00444.1	AKJ09_02182	AKJ09_07107	RNA polymerase sigma-54 factor RpoN; Belongs to the sigma-70 factor family. ECF subfamily.	RNA polymerase sigma factor RpoE; Belongs to the sigma-70 factor family. ECF subfamily.	0.408
AKU95518.1	AKV04369.1	AKJ09_02182	AKJ09_11032	RNA polymerase sigma-54 factor RpoN; Belongs to the sigma-70 factor family. ECF subfamily.	RNA polymerase sigma factor RpoE; Belongs to the sigma-70 factor family. ECF subfamily.	0.453
AKU95519.1	AKU95517.1	AKJ09_02183	AKJ09_02181	Putative signal peptide protein.	Hypothetical protein.	0.533
AKU95519.1	AKU95518.1	AKJ09_02183	AKJ09_02182	Putative signal peptide protein.	RNA polymerase sigma-54 factor RpoN; Belongs to the sigma-70 factor family. ECF subfamily.	0.533
AKU96572.1	AKU95518.1	AKJ09_03236	AKJ09_02182	RNA polymerase sigma factor RpoE; Belongs to the sigma-70 factor family. ECF subfamily.	RNA polymerase sigma-54 factor RpoN; Belongs to the sigma-70 factor family. ECF subfamily.	0.474
AKU98773.1	AKU95518.1	AKJ09_05437	AKJ09_02182	RNA polymerase sigma factor RpoE; Belongs to the sigma-70 factor family. ECF subfamily.	RNA polymerase sigma-54 factor RpoN; Belongs to the sigma-70 factor family. ECF subfamily.	0.407
AKV00444.1	AKU95518.1	AKJ09_07107	AKJ09_02182	RNA polymerase sigma factor RpoE; Belongs to the sigma-70 factor family. ECF subfamily.	RNA polymerase sigma-54 factor RpoN; Belongs to the sigma-70 factor family. ECF subfamily.	0.408
AKV04369.1	AKU95518.1	AKJ09_11032	AKJ09_02182	RNA polymerase sigma factor RpoE; Belongs to the sigma-70 factor family. ECF subfamily.	RNA polymerase sigma-54 factor RpoN; Belongs to the sigma-70 factor family. ECF subfamily.	0.453

Network Stats

number of nodes:

6

number of edges:

12

average node degree:

4

avg. local clustering coefficient:

0.9

expected number of edges:

5

PPI enrichment p-value:

0.0064

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006526

Arginine biosynthetic process

9 of 14

2.76

9.81

2.88e-20

GO:0046394

Carboxylic acid biosynthetic process

10 of 235

1.58

3.38

2.09e-13

GO:0006591

Ornithine metabolic process

3 of 3

2.95

3.17

1.57e-06

GO:0042450

Arginine biosynthetic process via ornithine

2 of 2

2.95

1.87

0.00040

GO:1901566

Organonitrogen compound biosynthetic process

10 of 576

1.19

1.75

5.53e-10

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003991

Acetylglutamate kinase activity

2 of 2

2.95

1.36

0.0035

GO:0008483

Transaminase activity

2 of 24

1.87

0.7

0.0464

GO:0036094

Small molecule binding

8 of 1136

0.8

0.6

0.0035

GO:0016740

Transferase activity

7 of 1222

0.71

0.46

0.0175

GO:0043168

Anion binding

6 of 1023

0.72

0.41

0.0464

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

10 of 2163

0.62

0.51

0.00038

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:7435

Arginine biosynthetic process

9 of 12

2.83

10.12

1.29e-20

CL:7439

Arginine biosynthesis

6 of 6

2.95

6.91

1.07e-13

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00220

Arginine biosynthesis

9 of 27

2.47

8.59

2.98e-19

map01210

2-Oxocarboxylic acid metabolism

6 of 52

2.01

3.96

6.63e-10

map01230

Biosynthesis of amino acids

9 of 187

1.63

3.47

1.50e-12

map01110

Biosynthesis of secondary metabolites

9 of 778

1.01

1.19

2.09e-07

map00250

Alanine, aspartate and glutamate metabolism

2 of 41

1.64

0.82

0.0227

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005622

Intracellular

9 of 2422

0.52

0.33

0.0406

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0055

Arginine biosynthesis

5 of 9

2.7

5.02

2.68e-10

KW-0963

Cytoplasm

5 of 265

1.23

1.13

0.00044

KW-0808

Transferase

6 of 489

1.04

0.93

0.00044

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