AKU99213.1 protein (Labilithrix luteola) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

AKU99213.1

Transcriptional regulator, AraC family. (260 aa)

Predicted Functional Partners:

AKU95037.1

0.760

AKU97964.1

0.749

AKU97858.1

0.748

AKU98709.1

0.748

AKU95707.1

0.728

AKU98369.1

0.726

AKV03954.1

0.691

AKU97887.1

0.676

AKU95823.1

0.639

AKU93810.1

0.603

Your Current Organism:

Labilithrix luteola

NCBI taxonomy Id: 1391654
Other names: DSM 27648, L. luteola, Labilithrix luteola Yamamoto et al. 2014, NBRC 109946, Sorangiineae bacterium B00002, strain B00002

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKU93810.1	AKU95037.1	AKJ09_00474	AKJ09_01701	Transcriptional regulator, AraC family.	Transcriptional regulator, AraC family.	0.677
AKU93810.1	AKU95823.1	AKJ09_00474	AKJ09_02487	Transcriptional regulator, AraC family.	Transcriptional regulator.	0.430
AKU93810.1	AKU97858.1	AKJ09_00474	AKJ09_04522	Transcriptional regulator, AraC family.	Transcriptional regulator, AraC family.	0.609
AKU93810.1	AKU97887.1	AKJ09_00474	AKJ09_04551	Transcriptional regulator, AraC family.	Transcriptional regulator, AraC family.	0.701
AKU93810.1	AKU98369.1	AKJ09_00474	AKJ09_05033	Transcriptional regulator, AraC family.	Putative TRANSCRIPTION REGULATOR PROTEIN.	0.648
AKU93810.1	AKU98709.1	AKJ09_00474	AKJ09_05373	Transcriptional regulator, AraC family.	Transcriptional regulator, AraC family.	0.741
AKU93810.1	AKU99213.1	AKJ09_00474	AKJ09_05877	Transcriptional regulator, AraC family.	Transcriptional regulator, AraC family.	0.603
AKU93810.1	AKV03954.1	AKJ09_00474	AKJ09_10617	Transcriptional regulator, AraC family.	DNA-binding response regulator, AraC family.	0.413
AKU95037.1	AKU93810.1	AKJ09_01701	AKJ09_00474	Transcriptional regulator, AraC family.	Transcriptional regulator, AraC family.	0.677
AKU95037.1	AKU98369.1	AKJ09_01701	AKJ09_05033	Transcriptional regulator, AraC family.	Putative TRANSCRIPTION REGULATOR PROTEIN.	0.770
AKU95037.1	AKU99213.1	AKJ09_01701	AKJ09_05877	Transcriptional regulator, AraC family.	Transcriptional regulator, AraC family.	0.760
AKU95037.1	AKV03954.1	AKJ09_01701	AKJ09_10617	Transcriptional regulator, AraC family.	DNA-binding response regulator, AraC family.	0.765
AKU95707.1	AKU97858.1	AKJ09_02371	AKJ09_04522	Transcriptional regulator, AraC family.	Transcriptional regulator, AraC family.	0.773
AKU95707.1	AKU99213.1	AKJ09_02371	AKJ09_05877	Transcriptional regulator, AraC family.	Transcriptional regulator, AraC family.	0.728
AKU95707.1	AKV03954.1	AKJ09_02371	AKJ09_10617	Transcriptional regulator, AraC family.	DNA-binding response regulator, AraC family.	0.725
AKU95823.1	AKU93810.1	AKJ09_02487	AKJ09_00474	Transcriptional regulator.	Transcriptional regulator, AraC family.	0.430
AKU95823.1	AKU98709.1	AKJ09_02487	AKJ09_05373	Transcriptional regulator.	Transcriptional regulator, AraC family.	0.668
AKU95823.1	AKU99213.1	AKJ09_02487	AKJ09_05877	Transcriptional regulator.	Transcriptional regulator, AraC family.	0.639
AKU95823.1	AKV03954.1	AKJ09_02487	AKJ09_10617	Transcriptional regulator.	DNA-binding response regulator, AraC family.	0.598
AKU97858.1	AKU93810.1	AKJ09_04522	AKJ09_00474	Transcriptional regulator, AraC family.	Transcriptional regulator, AraC family.	0.609

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

43

average node degree:

7.82

avg. local clustering coefficient:

0.86

expected number of edges:

25

PPI enrichment p-value:

0.0007

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006281

DNA repair

5 of 55

1.32

1.1

0.0014

GO:0006259

DNA metabolic process

7 of 154

1.02

0.86

0.0011

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0140097

Catalytic activity, acting on DNA

7 of 98

1.21

1.32

3.09e-05

GO:0008094

ATP-dependent activity, acting on DNA

4 of 41

1.35

0.99

0.0041

GO:0003677

DNA binding

8 of 255

0.86

0.74

0.00047

GO:0140664

ATP-dependent DNA damage sensor activity

2 of 6

1.88

0.69

0.0493

GO:0008408

3-5 exonuclease activity

2 of 7

1.82

0.68

0.0493

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:627

Mixed, incl. Mismatch repair, and DNA-templated DNA replication

9 of 39

1.72

3.72

4.28e-12

CL:678

SOS response, and Mutator protein

5 of 12

1.98

2.95

3.60e-07

CL:633

DNA-directed DNA polymerase, and HRDC domain

4 of 5

2.26

2.86

2.24e-06

CL:680

Holliday junction helicase complex, and DNA recombination and repair protein RecA-like, ATP-binding domain

3 of 6

2.06

1.78

0.00031

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03420

Nucleotide excision repair

4 of 18

1.71

1.7

0.00016

map03430

Mismatch repair

4 of 25

1.56

1.52

0.00025

map03440

Homologous recombination

3 of 42

1.21

0.65

0.0302

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0044815

DNA packaging complex

3 of 13

1.72

1.02

0.0089

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0234

DNA repair

5 of 31

1.57

1.85

2.09e-05

KW-0227

DNA damage

5 of 31

1.57

1.85

2.09e-05

KW-0235

DNA replication

3 of 17

1.61

1.16

0.0032

KW-0238

DNA-binding

8 of 180

1.01

1.04

2.09e-05

KW-0239

DNA-directed DNA polymerase

2 of 6

1.88

0.9

0.0183

(more ...)

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