STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpiARibose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (228 aa)    
Predicted Functional Partners:
hpsA
PFAM: Demethylmenaquinone methyltransferase; Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: 3-hexulose-6-phosphate synthase.
  
 
 0.913
KCZ73245.1
Sugar kinase, ribokinase; PFAM: pfkB family carbohydrate kinase.
    
 0.878
KCZ71463.1
Ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; N-terminal domain of ribose phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase.
  
 
 0.862
gap
PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II.
    
 0.844
KCZ72725.1
PFAM: SIS domain; TIGRFAM: 6-phospho 3-hexuloisomerase.
 
  
 0.837
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
 0.836
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
  
 0.817
fae-hps
Formaldehyde-activating enzyme; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the N-terminal section; belongs to the formaldehyde- activating enzyme family.
    
 0.804
KCZ71751.1
Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; TIGRFAM: phosphoglucosamine mutase; Belongs to the phosphohexose mutase family.
    
 0.781
KCZ70446.1
PFAM: F420-0:Gamma-glutamyl ligase; TIGRFAM: F420-0:gamma-glutamyl ligase.
  
 
 0.745
Your Current Organism:
Methanoperedens nitroreducens
NCBI taxonomy Id: 1392998
Other names: C. Methanoperedens nitroreducens, Candidatus Methanoperedens nitroreducens
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