STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCZ71964.1PFAM: Eukaryotic and archaeal DNA primase small subunit; TIGRFAM: DNA primase, eukaryotic-type, small subunit, putative. (478 aa)    
Predicted Functional Partners:
KCZ73151.1
PFAM: Eukaryotic and archaeal DNA primase, large subunit.
 
 0.999
KCZ72116.1
DNA polymerase elongation subunit (family B); PFAM: DNA polymerase family B; DNA polymerase family B, exonuclease domain.
   
 0.994
pcn
DNA polymerase sliding clamp subunit; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
 
 
 0.992
polB
Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family.
  
 0.946
rnhB
RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
 
  
 0.925
eif2a
PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain.
 
  
 0.922
KCZ71488.1
PFAM: ATPase family associated with various cellular activities (AAA).
  
 0.894
cdc6
ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication.
 
 
 0.889
fen
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...]
   
 
 0.888
KCZ71473.1
Putative ATPase involved in replication control, Cdc46/Mcm family; PFAM: MCM N-terminal domain; MCM2/3/5 family.
   
 0.882
Your Current Organism:
Methanoperedens nitroreducens
NCBI taxonomy Id: 1392998
Other names: C. Methanoperedens nitroreducens, Candidatus Methanoperedens nitroreducens
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