STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCZ70738.1Putative kinase, sugar kinase superfamily; PFAM: GHMP kinases N terminal domain. (284 aa)    
Predicted Functional Partners:
KCZ70737.1
PFAM: Protein of unknown function DUF137.
 
  
 0.986
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
    0.715
htpX
Heat shock protein; PFAM: Peptidase family M48; Belongs to the peptidase M48B family.
  
    0.702
htpX-2
Zn-dependent protease with chaperone function; PFAM: Peptidase family M48; Belongs to the peptidase M48B family.
  
    0.702
KCZ72036.1
Methionine synthase II (cobalamin-independent); PFAM: Cobalamin-independent synthase, Catalytic domain.
  
    0.693
KCZ70997.1
Zn-dependent protease with chaperone function; PFAM: Peptidase family M48.
  
    0.664
tfe
Transcription initiation factor IIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing [...]
  
    0.633
ytsJ
PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain.
  
    0.620
KCZ73343.1
PFAM: DNA / pantothenate metabolism flavoprotein; Flavoprotein; TIGRFAM: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase.
 
   
 0.593
KCZ72889.1
PFAM: ABC transporter; Possible Fer4-like domain in RNase L inhibitor, RLI; 4Fe-4S binding domain.
   
    0.579
Your Current Organism:
Methanoperedens nitroreducens
NCBI taxonomy Id: 1392998
Other names: C. Methanoperedens nitroreducens, Candidatus Methanoperedens nitroreducens
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