STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ahcYAdenosylhomocysteinase; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family. (418 aa)    
Predicted Functional Partners:
KCZ72036.1
Methionine synthase II (cobalamin-independent); PFAM: Cobalamin-independent synthase, Catalytic domain.
  
 
 0.956
KCZ71975.1
PFAM: Methylenetetrahydrofolate reductase.
  
 
 0.902
KCZ70911.1
Cystathionine beta-lyase/cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: methionine gamma-lyase; O-succinylhomoserine sulfhydrylase.
  
 0.867
KCZ70883.1
Adenylylsulfate kinase-like kinase; PFAM: Adenylylsulphate kinase.
     
 0.838
KCZ70884.1
Putative aminoglycoside phosphotransferase; PFAM: Phosphotransferase enzyme family.
       0.801
suhB
PFAM: Inositol monophosphatase family.
       0.789
KCZ72977.1
PFAM: Methyltransferase domain; Acetyltransferase (GNAT) domain.
  
 
 0.775
hom
PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain.
  
 
 0.769
KCZ72522.1
Dihydropteroate synthase-related protein; PFAM: Domain of unknown function (DUF4346); Pterin binding enzyme; TIGRFAM: dihydropteroate synthase-related protein.
    
 0.763
KCZ72823.1
Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V.
   
 
 0.763
Your Current Organism:
Methanoperedens nitroreducens
NCBI taxonomy Id: 1392998
Other names: C. Methanoperedens nitroreducens, Candidatus Methanoperedens nitroreducens
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