node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KCZ70462.1 | KCZ70463.1 | ANME2D_03377 | ANME2D_03378 | ACT domain-containing protein; PFAM: ACT domain; Belongs to the UPF0237 family. | Hypothetical protein; PFAM: Uncharacterised ACR (DUF711); Belongs to the UPF0210 family. | 0.943 |
KCZ70462.1 | KCZ71528.1 | ANME2D_03377 | ANME2D_02261 | ACT domain-containing protein; PFAM: ACT domain; Belongs to the UPF0237 family. | PFAM: CBS domain; Helix-turn-helix; putative transcriptional regulator with C-terminal CBS domains. | 0.738 |
KCZ70462.1 | KCZ72991.1 | ANME2D_03377 | ANME2D_00050 | ACT domain-containing protein; PFAM: ACT domain; Belongs to the UPF0237 family. | Aspartate kinase; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family. | 0.740 |
KCZ70462.1 | KCZ73027.1 | ANME2D_03377 | ANME2D_00086 | ACT domain-containing protein; PFAM: ACT domain; Belongs to the UPF0237 family. | Phosphatidylglycerophosphate synthase; PFAM: CDP-alcohol phosphatidyltransferase. | 0.735 |
KCZ70462.1 | KCZ73360.1 | ANME2D_03377 | ANME2D_00426 | ACT domain-containing protein; PFAM: ACT domain; Belongs to the UPF0237 family. | Archaetidylserine synthase; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; archaetidylserine synthase. | 0.722 |
KCZ70462.1 | glyA | ANME2D_03377 | ANME2D_03283 | ACT domain-containing protein; PFAM: ACT domain; Belongs to the UPF0237 family. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.790 |
KCZ70462.1 | hom | ANME2D_03377 | ANME2D_01738 | ACT domain-containing protein; PFAM: ACT domain; Belongs to the UPF0237 family. | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain. | 0.800 |
KCZ70462.1 | trpA | ANME2D_03377 | ANME2D_03220 | ACT domain-containing protein; PFAM: ACT domain; Belongs to the UPF0237 family. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.722 |
KCZ70462.1 | trpB-2 | ANME2D_03377 | ANME2D_03219 | ACT domain-containing protein; PFAM: ACT domain; Belongs to the UPF0237 family. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.723 |
KCZ70462.1 | trpF | ANME2D_03377 | ANME2D_01945 | ACT domain-containing protein; PFAM: ACT domain; Belongs to the UPF0237 family. | PFAM: N-(5'phosphoribosyl)anthranilate (PRA) isomerase; Belongs to the TrpF family. | 0.704 |
KCZ70463.1 | KCZ70462.1 | ANME2D_03378 | ANME2D_03377 | Hypothetical protein; PFAM: Uncharacterised ACR (DUF711); Belongs to the UPF0210 family. | ACT domain-containing protein; PFAM: ACT domain; Belongs to the UPF0237 family. | 0.943 |
KCZ71528.1 | KCZ70462.1 | ANME2D_02261 | ANME2D_03377 | PFAM: CBS domain; Helix-turn-helix; putative transcriptional regulator with C-terminal CBS domains. | ACT domain-containing protein; PFAM: ACT domain; Belongs to the UPF0237 family. | 0.738 |
KCZ71528.1 | KCZ72991.1 | ANME2D_02261 | ANME2D_00050 | PFAM: CBS domain; Helix-turn-helix; putative transcriptional regulator with C-terminal CBS domains. | Aspartate kinase; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family. | 0.722 |
KCZ71528.1 | glyA | ANME2D_02261 | ANME2D_03283 | PFAM: CBS domain; Helix-turn-helix; putative transcriptional regulator with C-terminal CBS domains. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.777 |
KCZ71528.1 | trpA | ANME2D_02261 | ANME2D_03220 | PFAM: CBS domain; Helix-turn-helix; putative transcriptional regulator with C-terminal CBS domains. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.726 |
KCZ71528.1 | trpB-2 | ANME2D_02261 | ANME2D_03219 | PFAM: CBS domain; Helix-turn-helix; putative transcriptional regulator with C-terminal CBS domains. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.723 |
KCZ71528.1 | trpF | ANME2D_02261 | ANME2D_01945 | PFAM: CBS domain; Helix-turn-helix; putative transcriptional regulator with C-terminal CBS domains. | PFAM: N-(5'phosphoribosyl)anthranilate (PRA) isomerase; Belongs to the TrpF family. | 0.737 |
KCZ72991.1 | KCZ70462.1 | ANME2D_00050 | ANME2D_03377 | Aspartate kinase; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family. | ACT domain-containing protein; PFAM: ACT domain; Belongs to the UPF0237 family. | 0.740 |
KCZ72991.1 | KCZ71528.1 | ANME2D_00050 | ANME2D_02261 | Aspartate kinase; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family. | PFAM: CBS domain; Helix-turn-helix; putative transcriptional regulator with C-terminal CBS domains. | 0.722 |
KCZ72991.1 | KCZ73027.1 | ANME2D_00050 | ANME2D_00086 | Aspartate kinase; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family. | Phosphatidylglycerophosphate synthase; PFAM: CDP-alcohol phosphatidyltransferase. | 0.435 |