STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrDDihydroorotate oxidase A; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (352 aa)    
Predicted Functional Partners:
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 0.988
SFV28167.1
Dihydroorotase.
  
 0.968
SFV29657.1
Dihydroorotase.
  
 0.968
SFV30650.1
Carbamoyl-phosphate synthase large subunit.
 
 0.958
SFV35612.1
Orotidine-5'-phosphate decarboxylase.
 
 
 0.952
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 
 0.941
carA
Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family.
 
  
 0.910
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
  
 0.857
pheT
phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.838
SFV31457.1
Glutamate synthase (NADPH/NADH) small chain.
  
 0.751
Your Current Organism:
Crenotalea thermophila
NCBI taxonomy Id: 1393122
Other names: C. thermophila, Chitinophagaceae bacterium STH-1-Y1, Crenotalea thermophila Hanada et al. 2014, DSM 14807, JCM 11541, strain STH-1-Y1
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