STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHB42538.15-formyltetrahydrofolate cyclo-ligase; RAAC3_TM7_1_669; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (162 aa)    
Predicted Functional Partners:
folD
FolD bifunctional protein, nonfunctional; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.935
pheT
Phenylalanine-tRNA ligase beta subunit; RAAC3_TM7_1_845; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.742
AHB42539.1
Potassium efflux system KefA protein / Small-conductance mechanosensitive channel; RAAC3_TM7_1_670.
       0.630
AHB42537.1
Hypothetical protein; RAAC3_TM7_1_668; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
  
    0.590
AHB42540.1
Hypothetical protein; RAAC3_TM7_1_671.
       0.505
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.452
Your Current Organism:
Saccharibacteria bacterium RAAC3TM71
NCBI taxonomy Id: 1394711
Other names: C. Saccharibacteria bacterium RAAC3_TM7_1, Candidatus Saccharibacteria bacterium RAAC3_TM7_1
Server load: low (22%) [HD]