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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CobAuroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 0.999
hemB
Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family.
 
 
 0.994
KLV16415.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.994
nirD
Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.966
KLV26920.1
Cobalamin biosynthesis protein CbiX; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.957
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.952
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.928
cobA
uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.928
cysI
Sulfite reductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.906
KLV26917.1
Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 0.901
Your Current Organism:
Bacillus circulans
NCBI taxonomy Id: 1397
Other names: ATCC 24, ATCC 4513, ATCC 9140, B. circulans, BCRC 10605, Bacillus sp. 3399BRRJ, Bacillus sp. NCIM 2107, Bacillus sp. NCIM 5045, Bacillus sp. NCIM 5046, CCM 2048, CCRC 10605, CCRC:10605, CCUG 7416, CIP 52.75, DSM 11, IAM 12462, IFO 13626, JCM 2504, LMG 13261, LMG 6926, LMG:13261, LMG:6926, NBRC 13626, NCCB 75011, NCIB 9374, NCIMB 9374, NCTC 2610, NRRL B-378, NRRL B-380
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