node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DnaN | dnaN | ABW02_01955 | ABW02_23615 | DNA polymerase III subunit beta; Binds the polymerase to DNA and acts as a sliding clamp; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.908 |
DnaN | polA | ABW02_01955 | ABW02_10155 | DNA polymerase III subunit beta; Binds the polymerase to DNA and acts as a sliding clamp; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.968 |
DnaN | recA | ABW02_01955 | ABW02_01110 | DNA polymerase III subunit beta; Binds the polymerase to DNA and acts as a sliding clamp; Derived by automated computational analysis using gene prediction method: Protein Homology. | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.772 |
KLV19585.1 | mutM | ABW02_23770 | ABW02_10160 | formamidopyrimidine-DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.922 |
KLV19585.1 | polA | ABW02_23770 | ABW02_10155 | formamidopyrimidine-DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.967 |
KLV24770.1 | KLV25636.1 | ABW02_17080 | ABW02_14750 | ATP-dependent dsDNA exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.924 |
KLV24770.1 | polA | ABW02_17080 | ABW02_10155 | ATP-dependent dsDNA exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.975 |
KLV24770.1 | recA | ABW02_17080 | ABW02_01110 | ATP-dependent dsDNA exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.605 |
KLV24770.1 | sbcD | ABW02_17080 | ABW02_17075 | ATP-dependent dsDNA exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.996 |
KLV25600.1 | polA | ABW02_15670 | ABW02_10155 | DNA polymerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.966 |
KLV25600.1 | recA | ABW02_15670 | ABW02_01110 | DNA polymerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.773 |
KLV25636.1 | KLV24770.1 | ABW02_14750 | ABW02_17080 | DNA repair exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent dsDNA exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.924 |
KLV25636.1 | KLV25702.1 | ABW02_14750 | ABW02_15125 | DNA repair exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.923 |
KLV25636.1 | polA | ABW02_14750 | ABW02_10155 | DNA repair exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.987 |
KLV25636.1 | recA | ABW02_14750 | ABW02_01110 | DNA repair exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.677 |
KLV25702.1 | KLV25636.1 | ABW02_15125 | ABW02_14750 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.923 |
KLV25702.1 | polA | ABW02_15125 | ABW02_10155 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.975 |
KLV25702.1 | recA | ABW02_15125 | ABW02_01110 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.605 |
KLV25702.1 | sbcD | ABW02_15125 | ABW02_17075 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.923 |
dnaN | DnaN | ABW02_23615 | ABW02_01955 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III subunit beta; Binds the polymerase to DNA and acts as a sliding clamp; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.908 |