STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A182M1X01-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1243 aa)    
Predicted Functional Partners:
A0A182LWS1
Uncharacterized protein.
    
0.965
A0A182M1Y6
Receptor protein-tyrosine kinase.
    
 0.949
A0A182MDL8
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
 0.946
A0A182M794
Uncharacterized protein.
    
 0.940
A0A182MV50
IPPc domain-containing protein.
     
 0.927
A0A182MB36
SH2 domain-containing protein.
   
 0.922
A0A182MQY9
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.921
A0A182LY84
Rho-GAP domain-containing protein.
    
 0.918
A0A182MAQ8
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.918
A0A182LW62
IPPc domain-containing protein.
    
 0.917
Your Current Organism:
Anopheles culicifacies
NCBI taxonomy Id: 139723
Other names: A. culicifacies
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