STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A182M6D53-hydroxy-3-methylglutaryl coenzyme A reductase. (785 aa)    
Predicted Functional Partners:
A0A182MTP9
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.979
A0A182M7P9
Mevalonate kinase.
  
 0.889
A0A182LY49
Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.
  
 
 0.834
A0A182MV33
Pyruvate carboxyltransferase domain-containing protein.
    
 0.779
A0A182LUX8
Uncharacterized protein.
   
 
 0.770
A0A182LXL3
RING-type domain-containing protein.
   
 
 0.669
A0A182MUQ9
Uncharacterized protein.
   
 
 0.669
A0A182ML36
BHLH domain-containing protein.
     
 0.616
A0A182M6F1
Uncharacterized protein; Belongs to the FPP/GGPP synthase family.
  
 
 0.603
A0A182M9T9
Nudix hydrolase domain-containing protein.
  
  
 0.603
Your Current Organism:
Anopheles culicifacies
NCBI taxonomy Id: 139723
Other names: A. culicifacies
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