STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A2C9GUI5Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2132 aa)    
Predicted Functional Partners:
A0A182M147
Uncharacterized protein.
   
 0.994
A0A182M7M1
Outer segment 4.
    
 0.808
A0A182M6X2
Outer segment 1.
   
 0.801
A0A182LTL5
Reduced mechanoreceptor potential A.
    
 0.793
A0A182MUJ7
Outer segment 6.
    
 0.793
A0A182MAP6
SH3 domain-containing protein.
   
 0.778
A0A182MCK9
GuKc domain-containing protein.
   
 0.778
A0A182LRD4
VWFA domain-containing protein.
   
 0.727
A0A182LW46
VGCC_alpha2 domain-containing protein.
   
 0.727
A0A182MB94
VWFA domain-containing protein.
   
 0.727
Your Current Organism:
Anopheles culicifacies
NCBI taxonomy Id: 139723
Other names: A. culicifacies
Server load: low (26%) [HD]