node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AB434_1125 | AB434_1213 | AB434_1125 | AB434_1213 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.481 |
AB434_1125 | AB434_1214 | AB434_1125 | AB434_1214 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase. | Dihydroneopterin aldolase. | 0.527 |
AB434_1125 | AB434_1215 | AB434_1125 | AB434_1215 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.593 |
AB434_1125 | AB434_3668 | AB434_1125 | AB434_3668 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase. | Dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. | 0.479 |
AB434_1125 | AB434_3696 | AB434_1125 | AB434_3696 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase. | Nucleoside 5-triphosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.469 |
AB434_1125 | folE | AB434_1125 | AB434_2955 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase. | GTP cyclohydrolase I. | 0.480 |
AB434_1125 | lysS | AB434_1125 | AB434_1216 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase. | Lysyl-tRNA synthetase (class II); Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.487 |
AB434_1125 | trpE | AB434_1125 | AB434_0236 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase. | Anthranilate synthase, aminase component; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high c [...] | 0.405 |
AB434_1213 | AB434_1125 | AB434_1213 | AB434_1125 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase. | 0.481 |
AB434_1213 | AB434_1214 | AB434_1213 | AB434_1214 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Dihydroneopterin aldolase. | 0.999 |
AB434_1213 | AB434_1215 | AB434_1213 | AB434_1215 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.999 |
AB434_1213 | AB434_3668 | AB434_1213 | AB434_3668 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. | 0.994 |
AB434_1213 | AB434_3696 | AB434_1213 | AB434_3696 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Nucleoside 5-triphosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.557 |
AB434_1213 | folE | AB434_1213 | AB434_2955 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | GTP cyclohydrolase I. | 0.988 |
AB434_1213 | lysS | AB434_1213 | AB434_1216 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Lysyl-tRNA synthetase (class II); Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.471 |
AB434_1213 | trpE | AB434_1213 | AB434_0236 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Anthranilate synthase, aminase component; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high c [...] | 0.615 |
AB434_1214 | AB434_1125 | AB434_1214 | AB434_1125 | Dihydroneopterin aldolase. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase. | 0.527 |
AB434_1214 | AB434_1213 | AB434_1214 | AB434_1213 | Dihydroneopterin aldolase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
AB434_1214 | AB434_1215 | AB434_1214 | AB434_1215 | Dihydroneopterin aldolase. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.999 |
AB434_1214 | AB434_3668 | AB434_1214 | AB434_3668 | Dihydroneopterin aldolase. | Dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. | 0.577 |