STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AB434_1947GTP pyrophosphokinase. (182 aa)    
Predicted Functional Partners:
rplK
LSU ribosomal protein L11p (L12e); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
 
 0.836
rplX
LSU ribosomal protein L24p (L26e); One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
  
   0.825
rpsF
SSU ribosomal protein S6p; Binds together with S18 to 16S ribosomal RNA.
  
 
 0.820
AB434_1268
SSU ribosomal protein S12p (S23e); Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
   
 
 0.810
rplD
LSU ribosomal protein L4p (L1e); Forms part of the polypeptide exit tunnel.
  
 
   0.807
rpsE
SSU ribosomal protein S5p (S2e); Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
   
 
 0.807
rpsJ
SSU ribosomal protein S10p (S20e); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
  
 
   0.805
rplI
LSU ribosomal protein L9p; Binds to the 23S rRNA.
  
 
   0.801
rplB
LSU ribosomal protein L2p (L8e); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
   0.801
rpsI
SSU ribosomal protein S9p (S16e); Belongs to the universal ribosomal protein uS9 family.
   
 
 0.801
Your Current Organism:
Bacillus coagulans
NCBI taxonomy Id: 1398
Other names: ATCC 7050, B. coagulans, BCRC 10606, Bacillus sp. NCIM 2323, CCM 2013, CCRC 10606, CCRC:10606, CCUG 7417, CFBP 4225, CIP 66.25, DSM 1, IFO 12583, IMET 10993, JCM 2257, LMG 6326, LMG:6326, Lactobacillus sp. T4, NBRC 12583, NCAIM B.01086, NCCB 48014, NCCB 77025, NCIB 9365, NCIMB 9365, NCTC 10334, NRRL NRS-609, VKM B-731
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